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  2. List of therapeutic monoclonal antibodies - Wikipedia

    en.wikipedia.org/wiki/List_of_therapeutic...

    This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.

  3. Checkpoint inhibitor - Wikipedia

    en.wikipedia.org/wiki/Checkpoint_inhibitor

    It was approved in 2014. Nivolumab is approved to treat melanoma, lung cancer, kidney cancer, bladder cancer, head and neck cancer, and Hodgkin's lymphoma. [16] Pembrolizumab (brand name Keytruda) is another PD-1 inhibitor that was approved by the FDA in 2014 and was the second checkpoint inhibitor approved in the United States. [17]

  4. Obecabtagene autoleucel - Wikipedia

    en.wikipedia.org/wiki/Obecabtagene_autoleucel

    Obecabtagene autoleucel, sold under the brand name Aucatzyl, is an anti-cancer medication used for the treatment of acute lymphoblastic leukemia. [ 1 ] [ 2 ] It is a CD19 -directed genetically modified autologous T-cell immunotherapy.

  5. US FDA approves Amgen drug for small cell lung cancer - AOL

    www.aol.com/news/us-fda-approves-amgen-drug...

    Amgen said the U.S. price for Imdelltra is $31,500 for the first cycle, and $30,000 for subsequent cycles. ... pivotal trial in advanced small cell lung cancer to receive full FDA approval of the ...

  6. PD-1 and PD-L1 inhibitors - Wikipedia

    en.wikipedia.org/wiki/PD-1_and_PD-L1_inhibitors

    The concept of blocking PD-1 and PD-L1 for the treatment of cancer was first published in 2001. [6] Pharmaceutical companies began attempting to develop drugs to block these molecules, and the first clinical trial was launched in 2006, evaluating nivolumab.

  7. Prescription drug prices in the United States - Wikipedia

    en.wikipedia.org/wiki/Prescription_drug_prices...

    The FDA has a "priority review process" for drugs which compete with another drug whose price exceeds its value-based price. Congress could also grant the FDA the ability to change the exclusivity period for new drugs. [6] The FDA could also temporarily allow the import of drugs approved for sale outside the United States. [65]

  8. Cancer treatment - Wikipedia

    en.wikipedia.org/wiki/Cancer_treatment

    Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]

  9. c-Met inhibitor - Wikipedia

    en.wikipedia.org/wiki/C-Met_inhibitor

    Crizotinib [2] and cabozantinib were the first to be approved by the U.S. FDA. Crizotinib received accelerated approval in 2011 for the treatment of patients with locally advanced or metastatic non-small cell lung cancer , while cabozantinib was approved in 2012 for the treatment of medullary thyroid cancer [ 3 ] and it has also started ...

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