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They have been marketed as herbal incense, or "herbal smoking blends", [6] and sold under common names such as K2, spice, [8] and synthetic marijuana. [5] They are often labeled "not for human consumption" for liability defense. [ 8 ]
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JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]
Butyl nitrite is the organic compound with the formula CH 3 (CH 2) 3 ONO. It is an alkyl nitrite made from n-butanol.Butyl nitrite is used recreationally as poppers.Synonyms include 1-butyl nitrite, n-butyl nitrite and nitrous acid butyl ester.
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Pharmaceutical compound Poppers A selection of over-the-counter poppers on display Clinical data Other names popper, poppe Routes of administration Inhalation Drug class Vasodilator Legal status Legal status AU: S4 (Prescription only) in general; some exceptions Elsewhere, usually available OTC Pharmacokinetic data Bioavailability When inhaled, Amyl nitrite: unknown Isopropyl nitrite: 43% ...
Mitragyna speciosa is a tropical evergreen tree of the Rubiaceae family (coffee family) native to Southeast Asia. [3] It is indigenous to Cambodia, Thailand, Indonesia, Malaysia, Myanmar, and Papua New Guinea, [4] where its leaves, known as kratom, have been used in herbal medicine since at least the 19th century. [5]
There is inconclusive clinical data whether specific vitamin K2 supplementation confers any beneficial effects compared to vitamin K1 which is the most common form in supplements. [1] In vitro studies show certain cellular effects of vitamin K2 in bone which are not observed with the K1 variant (including bone marrow stem cell (BMSC ...
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