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On July 12, 2016, 33 people were intoxicated by an herbal "incense" product called "AK-47 24 Karat Gold", [105] and dozens overdosed, in Brooklyn. Eighteen people were transported to local hospitals. [106] The herbal "incense" product was determined to be a synthetic cannabinoid called AMB-FUBINACA. [105]
Liquid chromatography (LC) techniques are also possible and, unlike GC methods, can differentiate between the acid and neutral forms of the cannabinoids. There have been systematic attempts to monitor the cannabinoid profile of cannabis over time, but their accuracy is impeded by the illegal status of the plant in many countries.
JWH-018 is a full agonist of both the CB 1 and CB 2 cannabinoid receptors, with a reported binding affinity of 9.00 ± 5.00 nM at CB 1 and 2.94 ± 2.65 nM at CB 2. [6] JWH-018 has an EC 50 of 102 nM for human CB 1 receptors, and 133 nM for human CB 2 receptors. [16]
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A homicide investigation is underway after three women were found dead inside a Columbus, Ohio residence over the weekend. On Saturday, Dec. 14 just before 4 p.m. local time, Columbus Police ...
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