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Rose spots on the abdomen of a man with typhoid fever. Paratyphoid fever resembles typhoid fever. Infection is characterized by a sustained fever, headache, abdominal pain, malaise, anorexia, a nonproductive cough (in early stage of illness), a relative bradycardia (slow heart rate), and hepatosplenomegaly (an enlargement of the liver and ...
Typhoid fever, also known simply as typhoid, is a disease caused by Salmonella enterica serotype Typhi bacteria, also called Salmonella typhi. [2] [3] Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. [4] [5] Often there is a gradual onset of a high fever over several days. [4]
Enteric fever is a medical term encompassing two types of salmonellosis, which, specifically, are typhoid fever and paratyphoid fever. [1] Enteric fever is a potentially life-threatening acute febrile systemic infection and is diagnosed by isolating a pathogen on culture.
Typhoid fever is caused by the bacterium Salmonella enterica Serovar Typhi. [ 37 ] In Canada alone, the typhus epidemic of 1847 killed more than 20,000 people from 1847 to 1848, mainly Irish immigrants in fever sheds and other forms of quarantine, who had contracted the disease aboard the crowded coffin ships in fleeing the Great Irish Famine .
The Vi capsular polysaccharide vaccine (or ViCPS) is a typhoid vaccine recommended by the World Health Organization for the prevention of typhoid (another is Ty21a).The vaccine was first licensed in the US in 1994 and is made from the purified Vi capsular polysaccharide from the Ty2 Salmonella Typhi strain; it is a subunit vaccine.
Diagnosis of continuous fever is usually based on the clinical signs and symptoms but some biological tests, chest X-ray and CT scan are also used. [2] Typhoid fever is an example of continuous fever and it shows a characteristic step-ladder pattern, a step-wise increase in temperature with a high plateau.
Outbreaks of typhoid fever are also frequently reported from sub-Saharan Africa and countries in Southeast Asia. [5] [6] [7] In the United States, about 400 cases occur each year, and 75% of these are acquired while traveling internationally. [8] [9] Historically, before the antibiotic era, the case fatality rate of typhoid
Typhoid fever is caused by Salmonella serotypes which are strictly adapted to humans or higher primates—these include Salmonella Typhi, Paratyphi A, Paratyphi B, and Paratyphi C. In the systemic form of the disease, salmonellae pass through the lymphatic system of the intestine into the blood of the patients (typhoid form) and are carried to ...