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Some recommend avoiding polytherapy and maintaining the minimal dose possible during pregnancy, but acknowledge that current data fails to demonstrate a dose effect on the risk of birth defects. [ 30 ] [ 31 ] Data now being collected by the Epilepsy and Antiepileptic Drug Pregnancy Registry may one day answer this question definitively.
Fetal hydantoin syndrome, also called fetal dilantin syndrome, is a group of defects caused to the developing fetus by exposure to teratogenic effects of phenytoin. Dilantin is the brand name of the drug phenytoin sodium in the United States, commonly used in the treatment of epilepsy .
Purple glove syndrome is caused by the intravenous anticonvulsant phenytoin. [3] This medication has many already established neurological side effects. However, glove syndrome is a rare, with prevalence ranging from 1.7% to 5.9%, but has very serious adverse effect that may lead to limb amputations.
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Use of anticonvulsant medications should be carefully monitored during use in pregnancy. [94] For example, since the first trimester is the most susceptible period for fetal development, planning a routine antiepileptic drug dose that is safer for the first trimester could be beneficial to prevent pregnancy complications. [95]
Your prescribing healthcare provider can make sure this GLP-1 (glucagon-like peptide-1) agonist drug is safe for you. If not, they can recommend an alternative weight loss drug .
Hydantoin, or glycolylurea, is a heterocyclic organic compound with the formula CH 2 C(O)NHC(O)NH. It is a colorless solid that arises from the reaction of glycolic acid and urea . It is an oxidized derivative of imidazolidine .
But some research has noted rare but serious side effects of once-weekly, 2.4 ... 0.5-milligram and 1-milligram doses of semaglutide resulted in an average heart rate ... Moving more each day.