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Inhibin is produced in the gonads, pituitary gland, placenta, corpus luteum and other organs. FSH stimulates the secretion of inhibin from the granulosa cells of the ovarian follicles in the ovaries. In turn, inhibin suppresses FSH. Inhibin B reaches a peak in the early- to mid-follicular phase, and a second peak at ovulation.
Follistatin is part of the inhibin-activin-follistatin axis. Three isoforms, FS-288, FS-300, and FS-315 have been reported. Two, FS-288 and FS-315, are created by alternative splicing of the primary mRNA transcript.
Inhibin, which is also secreted by the corpus luteum, contributes to FSH inhibition. Progesterone, secreted by the corpus luteum, inhibits the follicular growth and maintains the pregnancy. The endocrine system coincides with the menstrual cycle and goes through thirteen cycles (and thus thirteen LH spikes) during the course of normal ...
This increase in inhibin B, along with rising estrogen levels, contributes to the suppression of FSH secretion, which is critical for the selection of a single dominant follicle. As the cycle progresses to the luteal phase, inhibin A becomes the primary form produced by the corpus luteum.
The corpus luteum (Latin for "yellow body"; pl.: corpora lutea) is a temporary endocrine structure in female ovaries involved in the production of relatively high levels of progesterone, and moderate levels of estradiol, and inhibin A. [1] [2] It is the remains of the ovarian follicle that has released a mature ovum during a previous ovulation. [3]
anti-Müllerian hormone (AMH), secreted during the early stages of fetal life; inhibin and activins, secreted after puberty, work together to regulate FSH secretion; androgen-binding protein (also called testosterone-binding globulin) increases testosterone concentration in the seminiferous tubules to lightly stimulate spermatogenesis
Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. [1] FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland [2] and regulates the development, growth, pubertal maturation, and reproductive processes of the body.
They are responsible for the differentiation of spermatids, the maintenance of the blood-testis barrier, and the secretion of inhibin, androgen-binding protein and Müllerian-inhibiting factor. [citation needed] The organ of Corti in the inner ear and taste buds also contain sustentacular cells. [citation needed]