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A coma cocktail is a combination of substances administered in an emergency to comatose individuals when the cause of the coma has not yet been determined. [1] The intention is to work against various causes of a coma seen in an emergency setting including drug overdoses and hypoglycemia.
Clark's rule is a medical term referring to a mathematical formula used to calculate the proper dosage of medicine for children aged 2–17 based on the weight of the patient and the appropriate adult dose. [1] The formula was named after Cecil Belfield Clarke (1894–1970), a Barbadian physician who practiced throughout the UK, the West Indies ...
The IC 50 of a drug can be determined by constructing a dose-response curve and examining the effect of different concentrations of antagonist on reversing agonist activity. IC 50 values can be calculated for a given antagonist by determining the concentration needed to inhibit half of the maximum biological response of the agonist. [ 4 ]
Specifically, for drug dosing, the patient's length-based dosing zone can be adjusted up one color zone if the child appears overweight. Thus, incorporating a visual estimate of whether the child is overweight provides a simple method to predict actual patient weight that appears to be clinically relevant given the rise in obesity in the U.S ...
Absolute bioavailability refers to the bioavailability of a drug when administered via an extravascular dosage form (i.e. oral tablet, suppository, subcutaneous, etc.) compared with the bioavailability of the same drug administered intravenously (IV). This is done by comparing the AUC of the non-intravenous dosage form with the AUC for the drug ...
The 2025 FIFA Club World Cup is a 32-team tournament featuring top professional clubs from around the world, set to begin June 15, 2025, in the U.S. (Photo courtesy of FIFA)
These three changes have made my weight loss a success. No foods are bad foods. I was in the trap for so long of wanting to eat healthier and then eating too much junk food "for the last time." I ...
The study analyzed data from nearly 10,000 people who were enrolled in a randomized clinical trial, looking into the impact of low-dose aspirin on reducing heart disease risk in Australian and ...
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