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Deep lipomas have a greater tendency to recur than superficial lipomas because complete surgical removal of deep lipomas is not always possible. [37] [38] The presence of multiple lipomas, lipomatosis, is more commonly encountered in men. Some superficial lipomas can extend into deep fascia and may complicate excision.
The main treatment for lipomas is surgical excision, after which the tumor is examined with histopathology to confirm the diagnosis. [24] The prognosis for benign lipomas is excellent and recurrence after excision is rare, but may occur if the removal was incomplete. [25]
Reconstructive, medically necessary liposuction is used to treat lipedema, [7] to remove excess fat in the chronic medical condition lymphedema, [8] and to remove lipomas from areas of the body. [9] [10] Many articles refer to liposuction as "cosmetic" and not reimbursable by medical insurance companies. Most of this information is outdated.
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Removal can include simple excision, endoscopic removal, or liposuction. [ 1 ] Other entities which are accompanied by multiple lipomas include Proteus syndrome , Cowden syndrome and related disorders due to PTEN gene mutations, benign symmetric lipomatosis ( Madelung disease ), Dercum's Disease, familial lipodystrophy , hibernomas , epidural ...
The only effective treatments for lipomas caused by familial multiple lipomatosis are liposuction or surgical removal. [6] Steroid injections may also be used to shrink the tumors by causing local fat atrophy. [7] Patients with the condition often seek removal when the lipomas are large, disfiguring, or cause pain. [2]
Compared with Lilly’s Zepbound (tirzepatide), the once-daily experimental drug would be simpler to produce.
Lipedema is classified by stage: Stage 1: Normal skin surface with enlarged hypodermis (lipedema fat). Stage 2: Uneven skin with indentations in fat and larger hypodermal masses (lipomas). Stage 3: Bulky extrusions of skin and fat cause large deformations especially on the thighs and around the knees.