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Lupus occurs from infancy to old age, with peak occurrence between ages 15 and 40. [20] Lupus affects females in the US 6 to 10 times more often than males. [20] Prevalence data are limited. Estimates vary and range from 1.8 to 7.6 cases per 100,000 persons per year in parts of the continental United States. [20]
Often there are periods of illness, called flares, and periods of remission during which there are few symptoms. [1] Children up to 18 years old develop a more severe form of SLE termed childhood-onset systemic lupus erythematosus. [4] The cause of SLE is not clear. [1] It is thought to involve a combination of genetics and environmental ...
Other symptoms may include difficult or painful swallowing, new lumps or bumps in the neck, a swelling in the mouth, or a feeling of numbness in the mouth or lips. [8] Risk factors include tobacco and alcohol use. [9] [10] Those who use both alcohol and tobacco have a 15 times greater risk of oral cancer than those who use neither. [11]
Many symptoms are attributed to the development of Hashimoto's thyroiditis. Symptoms can include: fatigue, weight gain, pale or puffy face, feeling cold, joint and muscle pain, constipation, dry and thinning hair, heavy menstrual flow or irregular periods, depression, a slowed heart rate, problems getting pregnant, miscarriages, [19] and ...
It occurs most often in children and young adults between 5 and 19 years old. [62] In 2013, it resulted in about 161,000 deaths – down from 181,000 in 1990. [19] Infants, children, and adolescents in south-central and Southeast Asia have the highest rates of typhoid. [63] Outbreaks are also often reported in sub-Saharan Africa and Southeast Asia.
[17] [128] In such regions, as much as 90% of children younger than 10 years old have been infected and are immune, corresponding both to lower rates of clinically symptomatic disease and outbreaks. [ 105 ] [ 128 ] [ 129 ] The availability of a childhood vaccine has significantly reduced infections in the United States, with incidence declining ...
The Mayo Clinic, a world-renowned hospital based in Rochester, was founded by William Worrall Mayo, an immigrant from England. [140] [141] U.S. News & World Report 's 2020–21 survey ranked 4,554 hospitals in the country in 12 specialized fields of care, and placed the Mayo Clinic in the top four in most fields. The hospital ranked first on ...
A 2006 study in Denmark found that puberty, as evidenced by breast development, started at an average age of 9 years and 10 months, a year earlier than when a similar study was done in 1991. Scientists believe the phenomenon could be linked to obesity or exposure to chemicals in the food chain, and is putting females at greater long-term risk ...