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Periorbital cellulitis, or preseptal cellulitis, is an inflammation and infection of the eyelid and portions of skin around the eye anterior to the orbital septum. [1] It may be caused by breaks in the skin around the eye, and subsequent spread to the eyelid; infection of the sinuses around the nose (); or from spread of an infection elsewhere through the blood.
Orbital septum acts as a physical barrier that prevents the infection of the anterior part of the eye spreading posteriorly. For example, preseptal cellulitis mainly infects the eyelids, anterior to the orbital septum. Meanwhile, orbital cellulitis is located posterior the orbital septum, due to infections spreading from the ethmoidal sinuses.
Orbital cellulitis is an uncommon medical condition, with the reported rates being much higher among the pediatric population compared to the adult population. [3] One study reported that children are approximately 16 times more likely to suffer from orbital cellulitis compared to adults. [ 13 ]
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Cellulitis occurred in about 21.2 million people in 2015. [7] In the United States about 2 of every 1,000 people per year have a case affecting the lower leg. [1] Cellulitis in 2015 resulted in about 16,900 deaths worldwide. [8] In the United Kingdom, cellulitis was the reason for 1.6% of admissions to a hospital. [6]
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Here are links to possibly useful sources of information about Orbital cellulitis. PubMed provides review articles from the past five years (limit to free review articles) The TRIP database provides clinical publications about evidence-based medicine. Other potential sources include: Centre for Reviews and Dissemination and CDC