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Herpes simplex virus 1 (cold sores) and 2 (genital herpes) (HSV-1 and HSV-2) are two members of the human Herpesviridae family, a set of viruses that produce viral infections in the majority of humans. [1] [2] Both HSV-1 and HSV-2 are very common and contagious. They can be spread when an infected person begins shedding the virus.
Herpes simplex virus 1 infects humans, most often as cold sores. It is very common and contagious; about 67% of the world population under the age of 50 has Herpes simplex virus 1. [5] It is often acquired orally during childhood.
It is estimated to affect at least 1 in 500,000 individuals per year, [1] and some studies suggest an incidence rate of 5.9 cases per 100,000 live births. [2] About 90% of cases of herpes encephalitis are caused by herpes simplex virus-1 (HSV-1), the same virus that causes cold sores.
Nine herpesvirus types are known to primarily infect humans, [7] at least five of which are extremely widespread among most human populations, and which cause common diseases: herpes simplex 1 and 2 (HSV-1 and HSV-2, also known as HHV-1 and HHV-2; both of which can cause orolabial and genital herpes), varicella zoster (VZV or HHV-3; the cause ...
Herpes gladiatorum is a skin infection primarily caused by the herpes simplex virus. The virus infects the cells in the epidermal layer of the skin. The initial viral replication occurs at the entry site in the skin or mucous membrane. [7] The infections caused by a HSV Type 1 virus may be primary or recurrent. [8]
There are two types of herpes simplex virus, type 1 (HSV-1) and type 2 (HSV-2). [1] HSV-1 more commonly causes infections around the mouth while HSV-2 more commonly causes genital infections. [2] They are transmitted by direct contact with body fluids or lesions of an infected individual. [1] Transmission may still occur when symptoms are not ...
Herpes simplex virus 1 and 2, responsible for herpes simplex infections Human alphaherpesvirus 3 , also called varicella-zoster virus, responsible for chickenpox and shingles Human gammaherpesvirus 4 , or Epstein–Barr virus , one of the most common viruses which can cause various diseases
Infection by the type 1 strain of herpes simplex virus (HSV-1) is most common; however, cases of oral infection by the type 2 strain are increasing. [14] Oral HSV-2 shedding is rare, and "usually noted in the context of first episode genital herpes." [21] In general, both types can cause oral or genital herpes. [22] [23] [24]
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