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  2. B-cell receptor - Wikipedia

    en.wikipedia.org/wiki/B-cell_receptor

    A B-cell receptor includes both CD79 and the immunoglobulin. The plasma membrane of a B cell is indicated by the green phospholipids. The B- cell receptor extends both outside the cell (above the plasma membrane) and inside the cell (below the membrane). The B-cell receptor (BCR) is a transmembrane protein on the surface of a B cell.

  3. B-cell linker - Wikipedia

    en.wikipedia.org/wiki/B-cell_linker

    B-cell linker (BLNK) protein is expressed in B cells and macrophages and plays a large role in B cell receptor signaling. [5] Like all adaptor proteins , BLNK has no known intrinsic enzymatic activity. [ 6 ]

  4. B cell - Wikipedia

    en.wikipedia.org/wiki/B_cell

    B cells, unlike the other two classes of lymphocytes, T cells and natural killer cells, express B cell receptors (BCRs) on their cell membrane. [1] BCRs allow the B cell to bind to a foreign antigen, against which it will initiate an antibody response. [1] B cell receptors are extremely specific, with all BCRs on a B cell recognizing the same ...

  5. MHC class II - Wikipedia

    en.wikipedia.org/wiki/MHC_Class_II

    In humans, the MHC class II protein complex is encoded by the human leukocyte antigen gene complex (HLA). HLAs corresponding to MHC class II are HLA-DP, HLA-DM, HLA-DOA, HLA-DOB, HLA-DQ, and HLA-DR. Mutations in the HLA gene complex can lead to bare lymphocyte syndrome (BLS), which is a type of MHC class II deficiency.

  6. Protein kinase B - Wikipedia

    en.wikipedia.org/wiki/Protein_Kinase_B

    BAD is a pro-apoptotic protein of the Bcl-2 family. Akt1 can phosphorylate BAD on Ser136, [21] which makes BAD dissociate from the Bcl-2/Bcl-X complex and lose the pro-apoptotic function. [22] Akt1 can also activate NF-κB via regulating IκB kinase (IKK), thus result in transcription of pro-survival genes. [23]

  7. Major histocompatibility complex - Wikipedia

    en.wikipedia.org/wiki/Major_histocompatibility...

    In a cell, protein molecules of the host's own phenotype or of other biologic entities are continually synthesized and degraded. Each MHC molecule on the cell surface displays a small peptide (a molecular fraction of a protein) called an epitope. [3] The presented self-antigens prevent an organism's immune system from targeting its own cells ...

  8. Cytochrome b - Wikipedia

    en.wikipedia.org/wiki/Cytochrome_b

    Cytochrome b/b6 is an integral membrane protein of approximately 400 amino acid residues that probably has 8 transmembrane segments. In plants and cyanobacteria, cytochrome b6 consists of two protein subunits encoded by the petB and petD genes. Cytochrome b/b6 non-covalently binds two heme groups, known as b562 and b566.

  9. Protein Data Bank - Wikipedia

    en.wikipedia.org/wiki/Protein_Data_Bank

    The Protein Data Bank (PDB) [1] is a database for the three-dimensional structural data of large biological molecules such as proteins and nucleic acids, ...

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