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  2. Tofacitinib - Wikipedia

    en.wikipedia.org/wiki/Tofacitinib

    In 2023, the Institute for Clinical and Economic Review (ICER) identified Xeljanz as one of five high-expenditure drugs that experienced significant net price increases without new clinical evidence to justify the hikes. Specifically, Xeljanz's wholesale acquisition cost rose by 6%, leading to an additional $72 million in costs to U.S. payers. [38]

  3. Patented Medicine Prices Review Board - Wikipedia

    en.wikipedia.org/wiki/Patented_Medicine_Prices...

    Patented Medicine Prices Review Board office in Ottawa. Bill C-22, which was passed in 1987, established a compulsory licensing system under which drug patent holders were required to allow competing drug manufacturers to import their patented drug in exchange for a very modest 4% royalty, which resulted in an increase in the market share of generic drugs.

  4. The main difference is that patented drug prices in Canada average between 35% and 45% lower than in the United States, though generic prices are higher. [98] The price differential for brand-name drugs between the two countries has led Americans to purchase upward of $1 billion US in drugs per year from Canadian pharmacies. [99]

  5. Eculizumab - Wikipedia

    en.wikipedia.org/wiki/Eculizumab

    A 2014 Canadian study calculated the cost per life-year-gained with treatment as CAN$4.62 million (US$4,571,564) and cost per quality-adjusted-life-year as CAN$2.13 million (US$2,112,398)."The incremental cost per life year and per QALY gained is CAN$4.62 million and CAN$2.13 million, respectively.

  6. Prescription drug prices in the United States - Wikipedia

    en.wikipedia.org/wiki/Prescription_drug_prices...

    Prescription drug list prices in the United States continually are among the highest in the world. [1] [2] The high cost of prescription drugs became a major topic of discussion in the 21st century, leading up to the American health care reform debate of 2009, and received renewed attention in 2015.

  7. List of countries by total health expenditure per capita

    en.wikipedia.org/wiki/List_of_countries_by_total...

    Health care cost as percent of GDP (total economy of a nation). [2] [3] Graph below is life expectancy versus healthcare spending of rich OECD countries. US average of $10,447 in 2018. [7] See: list of countries by life expectancy.

  8. Tocilizumab - Wikipedia

    en.wikipedia.org/wiki/Tocilizumab

    Tocilizumab, sold under the brand name Actemra among others, is an immunosuppressive drug, used for the treatment of rheumatoid arthritis, systemic juvenile idiopathic arthritis, polyarticular juvenile idiopathic arthritis, giant cell arteritis, cytokine release syndrome, COVID‑19, and systemic sclerosis-associated interstitial lung disease (SSc-ILD).

  9. Healthcare in Canada - Wikipedia

    en.wikipedia.org/wiki/Healthcare_in_Canada

    This significantly influences Canada's healthcare services; [39] by 2019, Canada's aging population represented a modest increase in healthcare costs of about 1% a year. [ 7 ] Since the 2010s, Statistics Canada health research on aging has focused on "chronic diseases," "social isolation" and senior's mental health needs, and "transitions to ...