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Bipolar cells come in two varieties, having either an on-center or an off-center receptive field, each with a surround of the opposite sign. The off-center bipolar cells have excitatory synaptic connections with the photoreceptors, which fire continuously in the dark and are hyperpolarized (suppressed) by light. The excitatory synapses thus ...
Rod bipolar cells do not synapse directly on to ganglion cells. Instead, rod bipolar cells synapse on to a Retina amacrine cell, which in turn excite cone ON bipolar cells (via gap junctions) and inhibit cone OFF bipolar cells (via glycine-mediated inhibitory synapses) thereby overtaking the cone pathway in order to send signals to ganglion ...
The detailed explanation of the Reichardt-Hassenstain model will be provided later in the section. The anatomy of ON/OFF cells is such that the dendrites extend to two sublaminae of the inner plexiform layer and make synapses with bipolar and amacrine cells. They have four subtypes, each with its own preference for direction.
A retinal ganglion cell (RGC) is a type of neuron located near the inner surface (the ganglion cell layer) of the retina of the eye.It receives visual information from photoreceptors via two intermediate neuron types: bipolar cells and retina amacrine cells.
Diffuse bipolars can take signals from up to 50 rods or can be a flat cone form and take signals from seven cones. The bipolar cells corresponds to the intermediary cells between the touch and heat receptors on the skin and the medulla or spinal cord. [1]
So-called OFF bipolar cells are, like most neurons, excited by the released glutamate. However, neighboring target neurons called ON bipolar cells are instead inhibited by glutamate, because they lack typical ionotropic glutamate receptors and instead express a class of inhibitory metabotropic glutamate receptors. [21]
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Retinal summation describes the relationship between different types of cells in the retina: cone photoreceptor cells, bipolar cells, and ganglion cells.With high retinal summation, a large number of photoreceptor cells converge on a smaller number of bipolar cells in transferring their signals to ganglion cells.
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