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Poliomyelitis (/ ˌ p oʊ l i oʊ ˌ m aɪ ə ˈ l aɪ t ɪ s / POH-lee-oh-MY-ə-LY-tiss), commonly shortened to polio, is an infectious disease caused by the poliovirus. [1] Approximately 75% of cases are asymptomatic; [5] mild symptoms which can occur include sore throat and fever; in a proportion of cases more severe symptoms develop such as headache, neck stiffness, and paresthesia.
Only some infectious diseases leave behind permanent, highly visible, physical manifestation after an acute illness. Two of the most prominent were smallpox and polio—both largely conquered in ...
Poliomyelitis has existed for thousands of years, with depictions of the disease in ancient art. [1] The disease was first recognized as a distinct condition by the English physician Michael Underwood in 1789, [1] and the virus that causes it was first identified in 1908 by the Austrian immunologist Karl Landsteiner.
The protein has several domains of which domain D1 contains the polio virus binding site. Within this domain, 37 amino acids are responsible for binding the virus. Poliovirus is an enterovirus. Infection occurs via the fecal–oral route, meaning that one ingests the virus and viral replication occurs in the gastrointestinal tract. [42]
The virus infects the throat and intestines, and can cause flu-like symptoms. Paralysis from the polio virus is rare. This year, polio cases have been detected in New York state, London and Jerusalem.
The recent New York patient was infected with vaccine-derived polio, a strain linked to live virus from an oral polio vaccine not administered in the U.S. It marks the first U.S. of vaccine ...
Itzhak Perlman, a polio survivor, plays the violin while seated. Poliomyelitis (often simply called polio) is an acute viral infection that involves the gastrointestinal tract and occasionally the central nervous system. Poliovirus is acquired by faecal–oral or oral transmission.
With polio resurfacing, here are the facts on what was once was once one of the nation’s most feared diseases.