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  2. Rivaroxaban - Wikipedia

    en.wikipedia.org/wiki/Rivaroxaban

    Rivaroxaban, sold under the brand name Xarelto among others, is an anticoagulant medication (blood thinner) used to treat and prevent blood clots. [8] Specifically it is used to treat deep vein thrombosis and pulmonary emboli and prevent blood clots in atrial fibrillation and following hip or knee surgery. [ 8 ]

  3. Direct factor Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

    Antistasin, the first discovered naturally occurring direct Xa inhibitor Rivaroxaban, the first synthetic direct Xa inhibitor marketed as a drug Prior to the introduction of direct factor Xa inhibitors, vitamin K antagonists such as warfarin were the only oral anticoagulants for over 60 years, and together with heparin have been the main blood ...

  4. Discovery and development of direct Xa inhibitors - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    Rivaroxaban. During the SAR development of rivaroxaban, researchers realized that adding a 5-chlorothiophene-2-carboxamide group to the oxazolidonine core could increase the potency by 200 fold, which had previously been too weak for medical use. In addition to this discovery, a clear preference for the (S)-configuration was confirmed.

  5. Dailymotion - Wikipedia

    en.wikipedia.org/wiki/Dailymotion

    Dailymotion is a French online video sharing platform owned by Canal+. Prior to 2024, the company was owned by Vivendi . [ 2 ] North American launch partners included Vice Media , Bloomberg , and Hearst Digital Media . [ 3 ]

  6. List of online video platforms - Wikipedia

    en.wikipedia.org/wiki/List_of_online_video_platforms

    Other services have invested much time and effort into replicating the same functionality that has previously only been available via Windows Movie Maker, iMovie and other client-side applications that run outside of a web page. Some of these applications are based in AJAX and others in Flash.

  7. Intravenous regional anesthesia - Wikipedia

    en.wikipedia.org/wiki/Intravenous_regional...

    Shorter procedure times (for up to 2 hours) are preferred when IVRA is applied on the distal limb, especially on the forearm, except when the patient has contraindications to tourniquet use (such as in sickle cell anemia, where there is a risk of massive hemolysis due to low oxygen tension or hemolytic crisis due to restricted blood flow).

  8. X rating - Wikipedia

    en.wikipedia.org/wiki/X_rating

    Films may be shown in theaters in France only after classification by an administrative commission of the Ministry of Culture.In 1975, the X classification (officially: "pornographic or violence-inciting movies", films pornographiques ou d'incitation à la violence) was created for pornographic movies, or movies with successions of scenes of graphic violence.

  9. List of NC-17 rated films - Wikipedia

    en.wikipedia.org/wiki/List_of_NC-17_rated_films

    Swearnet: The Movie: 2014 Rated NC-17 for some explicit sexual content, graphic nudity and for language. [80] This One's For The Ladies: Uncensored: 2018 Uncensored version rated NC-17 for "some explicit sexual images" [81] Tie Me Up! Tie Me Down! 1989 Rated in 1990, the year the NC-17 rating was first introduced.