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A burning joint A joint prior to rolling, with a paper filter at left. A joint is a rolled cannabis cigarette.Unlike commercial tobacco cigarettes, the user ordinarily hand-rolls joints with rolling papers, though in some cases they are machine-rolled. [1]
[22] [23] It may be supplied as CBD oil containing only CBD as the active ingredient (excluding THC or terpenes), CBD-dominant hemp extract oil, capsules, dried cannabis, or prescription liquid solution. [4] [19] CBD does not have the same psychoactivity as THC, [24] [25] and can modulate the psychoactive effects of THC on the body if both are ...
It was also determined at that time that few horses with no chef-de-race influences in the two most stamina-laden groups, Solid and Professional, had won major races at distances of 1 + 1 ⁄ 4 miles or longer even if the horse had a sufficient Classic presence in its pedigree to keep the Dosage Index from being over 4.00 (when Affirmed won the ...
In July 2018, it became the first cannabis company to trade publicly on a major U.S. stock exchange, [13] opening on the NASDAQ exchange at a price of $17 per share, which increased in September 2018 to $214 per share, and then descended to $29 per share by August 2019. [14] [15] The IPO raised US$153 million. [16]
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In horses, this includes gastric ulcers, [8] right dorsal colitis, [9] and nephrotoxicity. [10] Flunixin is a prohibited substance under International Federation for Equestrian Sports rules, [11] and its use is prohibited or restricted by many other equestrian organizations. At labeled dose (1.1 mg/kg) given IV, detection time was found to be ...
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CBD is hydroxylated by P450 liver enzymes into 7-OH-CBD. Its metabolites are products of primarily CYP2C19 and CYP3A4 activity, with potential activity of CYP1A1, CYP1A2, CYP2C9, and CYP2D6. [69] Similar to delta-9-THC, a majority of CBD is excreted in feces and some in the urine. [57] The terminal half-life is approximately 18–32 hours. [70]