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Sialadenitis (sialoadenitis) is inflammation of salivary glands, usually the major ones, the most common being the parotid gland, followed by submandibular and sublingual glands. [1] It should not be confused with sialadenosis (sialosis) which is a non-inflammatory enlargement of the major salivary glands.
Salivary gland diseases (SGDs) are multiple and varied in cause. [1] There are three paired major salivary glands in humans: the parotid glands, the submandibular glands, and the sublingual glands. There are also about 800–1,000 minor salivary glands in the mucosa of the mouth.
Chronic sclerosing sialadenitis is a chronic (long-lasting) inflammatory condition affecting the salivary gland. Relatively rare in occurrence, this condition is benign, but presents as hard, indurated and enlarged masses that are clinically indistinguishable from salivary gland neoplasms or tumors.
About 85% of stones occur in the submandibular gland, [3] and 5–10% occur in the parotid gland. [2] In about 0–5% of cases, the sublingual gland or a minor salivary gland is affected. [2] When minor glands are rarely involved, caliculi are more likely in the minor glands of the buccal mucosa and the maxillary labial mucosa. [4]
The salivary glands in many vertebrates including mammals are exocrine glands that produce saliva through a system of ducts. Humans have three paired major salivary glands (parotid, submandibular, and sublingual), as well as hundreds of minor salivary glands. [1] Salivary glands can be classified as serous, mucous, or seromucous (mixed).
IgG4-related sialadenitis is particularly associated with involvement of one or both of the lacrimal glands (referred to as IgG4-related dacryo-sialadenitis). Mikulicz's disease, now considered to be a subtype of IgG4-related disease, [10] was a term used when (i) any two of the parotid, submandibular and lacrimal glands were persistently and ...
The sublingual gland (glandula sublingualis) is a seromucous polystomatic exocrine gland. Located underneath the oral diaphragm ( diaphragma oris ), the sublingual gland is the smallest and most diffuse of the three major salivary glands of the oral cavity, with the other two being the submandibular and parotid .
The Stafne defect (also termed Stafne's idiopathic bone cavity, Stafne bone cavity, Stafne bone cyst (misnomer), lingual mandibular salivary gland depression, lingual mandibular cortical defect, latent bone cyst, or static bone cyst) is a depression of the mandible, most commonly located on the lingual surface (the side nearest the tongue).