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Intensive insulin therapy or flexible insulin therapy is a therapeutic regimen for diabetes mellitus treatment. This newer approach contrasts with conventional insulin therapy. Rather than minimize the number of insulin injections per day (a technique which demands a rigid schedule for food and activities), the intensive approach favors ...
First described in 1934, [59] what physicians typically refer to as sliding-scale insulin (SSI) is fast- or rapid-acting insulin only, given subcutaneously, typically at meal times and sometimes bedtime, [60] but only when blood glucose is above a threshold (e.g. 10 mmol/L, 180 mg/dL). [61]
"Management of diabetes mellitus in hospitalized patients: efficiency and effectiveness of sliding-scale insulin therapy". Pharmacotherapy. 26 (10): 1421–32. PMID 16999652. Queale, WS; Seidler, AJ; Brancati, FL (Mar 10, 1997). "Glycemic control and sliding scale insulin use in medical inpatients with diabetes mellitus". Archives of internal ...
In 1927, Sakel, who had recently qualified as a medical doctor in Vienna and was working in a psychiatric clinic in Berlin, began to use low (sub-coma) doses of insulin to treat drug addicts and psychopaths, and when one of the patients experienced improved mental clarity after having slipped into an accidental coma, Sakel reasoned the treatment might work for mentally ill patients. [3]
sliding scale insulin or sliding scale regular insulin: mistaken to mean "strong solution of iodine" or "selective serotonin reuptake inhibitor". See also SSRI: SQ subcutaneously "SQ" can be mistaken for "5Q" meaning "5 every dose". See also SC: SSRI selective serotonin reuptake inhibitor [or] sliding scale regular insulin: ambiguous. Do not ...
Conventional insulin therapy is characterized by: Insulin injections of a mixture of regular (or rapid) and intermediate acting insulin are performed two times a day, or to improve overnight glucose, mixed in the morning to cover breakfast and lunch, but with regular (or rapid) acting insulin alone for dinner and intermediate acting insulin at bedtime (instead of being mixed in at dinner).
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