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Increasing numbers of regulatory submissions for new drugs provide PRO data to support claims. DeMuro et al. (2013) [26] have reviewed drug approvals for the years 2006–2010. They showed that of 75 drugs approved by both agencies, 35 (47%) had at last one PRO-related claim approved by the EMA compared to 14 (19%) for the FDA.
In April 2021, a group at Kyoto University reported a case of Lance Adams syndrome 11 years after onset due to hypoxic encephalopathy caused by a bronchial asthma attack, and in March 2022, a group at Kitasato University reported a case of Lance Adams syndrome after a hanging neck injury 1 year and 6 months after onset. There are an increasing ...
ADAMs (short for a disintegrin and metalloproteinase) are a family of single-pass transmembrane and secreted metalloendopeptidases. [1] [2] All ADAMs are characterized by a particular domain organization featuring a pro-domain, a metalloprotease, a disintegrin, a cysteine-rich, an epidermal-growth factor like and a transmembrane domain, as well as a C-terminal cytoplasmic tail. [3]
Journal of Clinical Medicine is a medical journal that covers clinical and pre-clinical research. Topics of interest include cardiology , gastroenterology & hepatopancreatobiliary medicine, clinical neurology etc.
The International Journal of Clinical and Experimental Medicine is an open access medical journal established in 2008. [1] It covers all areas of experimental and clinical medicine and publishes review articles, original articles, case reports, and editorials. It is published by e-Century Publishing Corporation.
Adams is a cardiac surgeon at Mount Sinai Hospital in New York City, specializing in mitral valve repair.He is the author of over 800 publications (as of April 2020), [8] holds three patents (Patent number 7.959.673, 6.660.265 and 6.540.781) and is recognized as a leading surgeon scientist and medical expert, serving on the Editorial Boards of several medical journals, including the Annals of ...
As widespread use of AI in healthcare is relatively new, research is ongoing into its application in various subdisciplines of medicine and related industries. AI programs are applied to practices such as diagnostics, [4] treatment protocol development, [5] drug development, [6] personalized medicine, [7] and patient monitoring and care. [8]
[96] [97] [98] An example of all these problems can be seen in a Cochrane Review, [99] as analyzed by Edmund J. Fordham, et al. in their relevant review. [96] A lag exists between when the RCT is conducted and when its results are published. [100] A lag exists between when results are published and when they are properly applied. [101]