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Thus, to Barcroft homeostasis was not only organized by the brain—homeostasis served the brain. [12] Homeostasis is an almost exclusively biological term, referring to the concepts described by Bernard and Cannon, concerning the constancy of the internal environment in which the cells of the body live and survive.
An example of positive feedback mechanism in the insulin transduction pathway is the activation of some enzymes that inhibit other enzymes from slowing or stopping the insulin transduction pathway which results in improved intake of the glucose. One of these pathways, involves the PI(3)K enzyme (Phosphoinositide 3-kinase). This pathway is ...
Mathematically, positive feedback is defined as a positive loop gain around a closed loop of cause and effect. [1][3] That is, positive feedback is in phase with the input, in the sense that it adds to make the input larger. [4][5] Positive feedback tends to cause system instability. When the loop gain is positive and above 1, there will ...
In humans, the pituitary gland is located at the base of the brain, protruding off the bottom of the hypothalamus. The human pituitary gland is oval shaped, about 1 cm in diameter, 0.5–1 gram (0.018–0.035 oz) in weight on average, and about the size of a kidney bean. [2][3]
Autoregulation. Autoregulation is a process within many biological systems, resulting from an internal adaptive mechanism that works to adjust (or mitigate) that system's response to stimuli. While most systems of the body show some degree of autoregulation, it is most clearly observed in the kidney, the heart, and the brain. [1] Perfusion of ...
Up-regulation is a process which occurs within a cell triggered by a signal (originating internal or external to the cell), which results in increased expression of one or more genes and as a result the proteins encoded by those genes. Conversely, down-regulation is a process resulting in decreased gene and corresponding protein expression.
In physiology, a stimulus[1] is a change in a living thing's internal or external environment. This change can be detected by an organism or organ using sensitivity, and leads to a physiological reaction. [2] Sensory receptors can receive stimuli from outside the body, as in touch receptors found in the skin or light receptors in the eye, as ...
t. e. Acid–base homeostasis is the homeostatic regulation of the pH of the body's extracellular fluid (ECF). [1] The proper balance between the acids and bases (i.e. the pH) in the ECF is crucial for the normal physiology of the body—and for cellular metabolism. [1] The pH of the intracellular fluid and the extracellular fluid need to be ...