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  2. United States drug overdose death rates and totals over time

    en.wikipedia.org/wiki/United_States_drug...

    A two milligram dose of fentanyl powder (on pencil tip) is a lethal amount for most people. [ 3 ] The United States Centers for Disease Control and Prevention (CDC) has data on drug overdose death rates and totals. Around 1,106,900 US residents died from drug overdoses from 1968 to 2020. Around 932,400 died from 1999 through 2020.

  3. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

  4. Drugs in the United States - Wikipedia

    en.wikipedia.org/wiki/Drugs_in_the_United_States

    In the United States, the Federal Food, Drug, and Cosmetic Act defined the word "drug" as an "article intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in man or other animals" and those " (other than food) intended to affect the structure or any function of the body of man or other animals." [2]

  5. Substance abuse - Wikipedia

    en.wikipedia.org/wiki/Substance_abuse

    Substance abuse, also known as drug abuse, is the use of a drug in amounts or by methods that are harmful to the individual or others. It is a form of substance-related disorder. Differing definitions of drug abuse are used in public health, medical, and criminal justice contexts. In some cases, criminal or anti-social behavior occurs when the ...

  6. Opioid epidemic in the United States - Wikipedia

    en.wikipedia.org/wiki/Opioid_epidemic_in_the...

    Total drug overdose deaths in the United States. There is an ongoing opioid epidemic (also known as the opioid crisis) in the United States, originating out of both medical prescriptions and illegal sources. It has been called "one of the most devastating public health catastrophes of our time". The opioid epidemic unfolded in three waves.

  7. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    List of polysubstance combinations. A drug combination chart designed for harm reduction by TripSit [1] Polysubstance use or multisubstance use is the use of combinations of psychoactive substances with both legal and illegal substances. This page lists polysubstance combinations that are entheogenic, recreational, or off-label indicated use of ...

  8. Opioid epidemic - Wikipedia

    en.wikipedia.org/wiki/Opioid_epidemic

    Opioid epidemic. The opioid epidemic, also referred to as the opioid crisis, is the rapid increase in the overuse, misuse/abuse, and overdose deaths attributed either in part or in whole to the class of drugs called opiates / opioids since the 1990s. It includes the significant medical, social, psychological, demographic and economic ...

  9. National Institute on Drug Abuse - Wikipedia

    en.wikipedia.org/wiki/National_Institute_on_Drug...

    nida.nih.gov. The National Institute on Drug Abuse (NIDA) is a United States federal government research institute whose mission is to "advance science on the causes and consequences of drug use and addiction and to apply that knowledge to improve individual and public health." The institute has conducted an in-depth study of addiction ...

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