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Endocrine disorders are often quite complex, involving a mixed picture of hyposecretion and hypersecretion because of the feedback mechanisms involved in the endocrine system. For example, most forms of hyperthyroidism are associated with an excess of thyroid hormone and a low level of thyroid stimulating hormone .
Endocrinology (from endocrine + -ology) is a branch of biology and medicine dealing with the endocrine system, its diseases, and its specific secretions known as hormones.It is also concerned with the integration of developmental events proliferation, growth, and differentiation, and the psychological or behavioral activities of metabolism, growth and development, tissue function, sleep ...
The study of the endocrine system and its disorders is known as endocrinology. The thyroid secretes thyroxine, the pituitary secretes growth hormone, the pineal secretes melatonin, the testis secretes testosterone, and the ovaries secrete estrogen and progesterone. [2]
BMC Endocrine Disorders is a peer-reviewed open-access medical journal covering research in all aspects of the prevention, diagnosis, and management of endocrine disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
Generally, diseases outlined within the ICD-10 codes E00-E35 within Chapter IV: Endocrine, nutritional and metabolic diseases should be included in this category. Subcategories This category has the following 12 subcategories, out of 12 total.
It causes the dysfunction of multiple endocrine glands due to autoimmunity. It is a genetic disorder, inherited in autosomal recessive fashion due to a defect in the AIRE gene (autoimmune regulator), which is located on chromosome 21 and normally confers immune tolerance. [1] [2] [3]
[7] [8] Furthermore, the human leukocyte antigen involved in this condition are HLA-DQ2(DR3 (DQB*0201)) and HLA-DQ8(DR4 (DQB1*0302)), [9] genetically speaking, which indicates this is a multifactorial disorder, as well. [1] [10] Should any affected organs show chronic inflammatory infiltrate (lymphocytes), this would be an indication.
The thyroid, parathyroid, pituitary, or adrenal glands, and the pancreas are parts of the endocrine system, and, therefore are associated with the endocrine bone disease. [2] Some common endocrine disorders are hypothyroidism, hyperthyroidism, Paget's disease, [1] Osteoporosis, and diabetes. [3]
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