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A coherent theory of neutral evolution was first proposed by Motoo Kimura in 1968 [9] and by King and Jukes independently in 1969. [10] Kimura initially focused on differences among species; King and Jukes focused on differences within species. Many molecular biologists and population geneticists also contributed to the development of the ...
The Neutral Theory of Molecular Evolution is an influential monograph written in 1983 by Japanese evolutionary biologist Motoo Kimura.While the neutral theory of molecular evolution existed since his article in 1968, [1] Kimura felt the need to write a monograph with up-to-date information and evidences showing the importance of his theory in evolution.
Neutral mutation has become a part of the neutral theory of molecular evolution, proposed in the 1960s. This theory suggests that neutral mutations are responsible for a large portion of DNA sequence changes in a species. For example, bovine and human insulin, while differing in amino acid sequence are still able to perform the same function ...
Non-Darwinian Evolution" is a scientific paper written by Jack Lester King and Thomas H. Jukes and published in 1969. It is credited, along with Motoo Kimura's 1968 paper "Evolutionary Rate at the Molecular Level", with proposing what became known as the neutral theory of molecular evolution.
Neutral evolution can therefore be visualised as a population diffusing from one set of sequence nodes, through the neutral network, to another cluster of sequence nodes. Since the majority of evolution is thought to be neutral, [ 14 ] [ 15 ] a large proportion of gene change is the movement though expansive neutral networks.
Alternatives to Darwinian evolution have been proposed by scholars investigating biology to explain signs of evolution and the relatedness of different groups of living things. The alternatives in question do not deny that evolutionary changes over time are the origin of the diversity of life, nor that the organisms alive today share a common ...
The neutral theory of evolution proposes that diversity is the result of the accumulation of neutral substitutions. Diversifying selection is the hypothesis that two subpopulations of a species live in different environments that select for different alleles at a particular locus. This may occur, for instance, if a species has a large range ...
In the late 1960s, the neutral theory of molecular evolution provided a theoretical basis for the molecular clock, though both the clock and the neutral theory were controversial, since most evolutionary biologists held strongly to panselectionism, with natural selection as the only important cause of evolutionary change.