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A scanner used to measure bone density using dual energy X-ray absorptiometry. Bone density, or bone mineral density, is the amount of bone mineral in bone tissue.The concept is of mass of mineral per volume of bone (relating to density in the physics sense), although clinically it is measured by proxy according to optical density per square centimetre of bone surface upon imaging. [1]
Bone density. The basic principle of single-photon bone mineral density measuring instrument is to calculate the attenuation degree of single-energy gamma photon beam through bone tissue. The more attenuation degree is, the more absorbed by bone minerals, the more bone mineral content and the higher bone mineral density are.
MDCalc is a free online medical reference for healthcare professionals that provides point-of-care clinical decision-support tools, including medical calculators, scoring systems, and algorithms. [1]
Bone densities are often given to patients as a T score or a Z score. A T score tells the patient what their bone mineral density is in comparison to a young adult of the same gender with peak bone mineral density. A normal T score is -1.0 and above, low bone density is between -1.0 and -2.5, and osteoporosis is -2.5 and lower.
DXA is only able to provide the areal bone mineral density. High-resolution peripheral quantitative computed tomography (HR-pQCT) is better than DXA at detecting bone microarchitecture, modeling whole-bone geometry using 3-dimensional information from scans. This method allows estimation of bone strength and other mechanical properties. [20]
The trabecular bone score is a measure of bone texture correlated with bone microarchitecture and a marker for the risk of osteoporosis. Introduced in 2008, [ 1 ] its main projected use is alongside measures of bone density in better predicting fracture risk in people with metabolic bone problems.
In adults there may be decreased muscle mass, high cholesterol levels, or poor bone density. [1] GHD can be present at birth or develop later in life. [1] Causes may include genetics, trauma, infections, tumors, or radiation therapy. [2] Genes that may be involved include GH1, GHRHR, or BTK. [3] In a third of cases no cause is apparent. [2]
In particular, physical exercise can be beneficial for bone density in postmenopausal women, [140] and lead to a slightly reduced risk of a bone fracture (absolute difference 4%). [141] Weight bearing exercise has been found to cause an adaptive response in the skeleton, [142] promoting osteoblast activity and protecting bone density. [143]