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  2. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    Gabapentinoid. Gabapentinoids, also known as α2δ ligands, are a class of drugs that are derivatives of the inhibitory neurotransmitter gamma-Aminobutyric acid (GABA) (i.e., GABA analogues) which block α 2 δ subunit -containing voltage-dependent calcium channels (VDCCs). [1][2][3][4] This site has been referred to as the gabapentin receptor ...

  3. Pregabalin - Wikipedia

    en.wikipedia.org/wiki/Pregabalin

    Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD). [13] [17] [18] Pregabalin also has antiallodynic properties.

  4. Gabapentin - Wikipedia

    en.wikipedia.org/wiki/Gabapentin

    Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat partial seizures and neuropathic pain. [7][10] It is a commonly used medication for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central pain. [11]

  5. Anticonvulsant - Wikipedia

    en.wikipedia.org/wiki/Anticonvulsant

    Anticonvulsants (also known as antiepileptic drugs, antiseizure drugs, or anti-seizure medications (ASM)) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. [1] Anticonvulsants are also increasingly being used in the treatment of bipolar disorder [2][3] and borderline personality disorder, [4] since many ...

  6. GABA analogue - Wikipedia

    en.wikipedia.org/wiki/GABA_analogue

    GABA analogue. γ-Aminobutyric acid (GABA) A GABA analogue is a compound which is an analogue or derivative of the neurotransmitter gamma-Aminobutyric acid (GABA) (the IUPAC of which is 4-aminobutanoic acid). Many GABA analogues are used as drugs, especially as anticonvulsants, sedatives, and anxiolytics.

  7. 4-Methylpregabalin - Wikipedia

    en.wikipedia.org/wiki/4-Methylpregabalin

    4-Methylpregabalin. 4-Methylpregabalin is a drug developed by Pfizer and related to pregabalin, which similarly acts as an analgesic with effectiveness against difficult to treat "atypical" pain syndromes such as neuropathic pain. The effectiveness of pregabalin and its older relative gabapentin against pain syndromes of this kind (which tend ...

  8. Voltage-gated calcium channel - Wikipedia

    en.wikipedia.org/wiki/Voltage-gated_calcium_channel

    Voltage-gated calcium channels (VGCCs), also known as voltage-dependent calcium channels (VDCCs), are a group of voltage-gated ion channels found in the membrane of excitable cells (e.g. muscle, glial cells, neurons) with a permeability to the calcium ion Ca 2+. [1][2] These channels are slightly permeable to sodium ions, so they are also ...

  9. Epilepsy in animals - Wikipedia

    en.wikipedia.org/wiki/Epilepsy_in_animals

    Epilepsy in animals is a group of neurological disorders characterized by seizures, caused by uncontrolled, abnormal bursts of electrical activity in the brain. They can start and stop very abruptly and last any amount of time from a few seconds to a few minutes. [ 1] Canine epilepsy is often genetic but epilepsy in cats and other pets is rarer ...

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