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Cytomegalovirus retinitis, also known as CMV retinitis, is an inflammation of the retina of the eye that can lead to blindness. [1] Caused by human cytomegalovirus , it occurs predominantly in people whose immune system has been compromised, including 15-40% of those with AIDS.
The retina is the eye's "sensing" tissue. Retinitis may be caused by a number of different infectious agents. Its most common form, called retinitis pigmentosa, has a prevalence of one in every 2,500–7,000 people. This condition is one of the leading causes that leads to blindness in patients in the age range of 20–60 years old.
Cytomegalovirus (CMV) (from cyto-'cell' via Greek κύτος kútos - 'container' + μέγας mégas 'big, megalo-' + -virus via Latin vīrus 'poison') is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, [3] in the subfamily Betaherpesvirinae. Humans and other primates serve as natural hosts.
A unilateral decrease in visual acuity is the most common symptom of toxoplasmic retinitis. Under ophthalmic examination, toxoplasmic chorioretinitis classically appears as a focal, white retinitis with overlying moderate inflammation of the vitreous humour. The inflamed vitreous, when it obscures the view of the fundus, is described as having ...
CMV is really common—more than half of adults have been infected with it by age 40, according to the Centers for Disease Control and Prevention (CDC). Most people with CMV show no symptoms, but ...
Cytomegalovirus (CMV) retinitis: Retinitis, vitritis, or uveitis. Retinitis usually occurs at the site of previous CMV retinitis lesions; Presence of vitritis or uveitis may help distinguish IRIS from active CMV retinitis; May cause rapid and permanent vision loss; Hepatitis B or Hepatitis C virus May be difficult to distinguish from drug ...
Bulging eyes: where the eye (one or both) protrudes or distends out of its orbit. Left untreated, bulging eyes may lead to eye dryness, pain and vision loss [3] Cytomegalovirus (CMV) Retinitis: This is an inflammation of the retina caused by infection, which can result in blindness.
Micrograph of CMV placentitis. One cell on the image (centre) has the characteristic large nucleus with peri-nuclear clearing. Two cells (centre-right) have the characteristic (cytoplasmic) viral inclusion bodies (small pink globules). H&E stain. CMV infection can be demonstrated microscopically by the detection of intranuclear inclusion bodies.
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