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  2. Gefapixant - Wikipedia

    en.wikipedia.org/wiki/Gefapixant

    Gefapixant, sold under the brand name Lyfnua, is a medication used to treat chronic (long-term) cough. [1] It acts as an antagonist of the P2RX3 receptor. [2] [3] [4]

  3. US FDA declines to approve Merck's chronic cough drug - AOL

    www.aol.com/news/us-fda-declines-approve-mercks...

    Merck's gefapixant works by blocking receptors that stimulate the nerves and trigger the urge to cough. The drug, which was given twice a day, was evaluated across two late-stage trials where a ...

  4. Guaifenesin/codeine - Wikipedia

    en.wikipedia.org/wiki/Guaifenesin/codeine

    Guaifenesin/codeine is a fixed-dose combination cold medicine used for the treatment of cough. [1] It contains guaifenesin, an expectorant; and codeine, as the phosphate, an opioid antitussive. [1]

  5. Benzonatate - Wikipedia

    en.wikipedia.org/wiki/Benzonatate

    Benzonatate is a prescription non-opioid alternative for the symptomatic relief of cough.[7] [9] It has been found to improve cough associated with a variety of respiratory conditions including asthma, bronchitis, pneumonia, tuberculosis, pneumothorax, opioid-resistant cough in lung cancer, and emphysema.

  6. US FDA staff flags concerns on Merck's chronic cough drug - AOL

    www.aol.com/news/us-fda-staff-flags-concerns...

    The panel will deliberate whether the data provided by Merck establishes that a small reduction in cough frequency with the use of gefapixant is clinically meaningful to patients. US FDA staff ...

  7. Oxomemazine/guaifenesin - Wikipedia

    en.wikipedia.org/wiki/Oxomemazine/guaifenesin

    This pharmacology -related article is a stub. You can help Wikipedia by expanding it.

  8. Hydrocodone/guaifenesin - Wikipedia

    en.wikipedia.org/wiki/Hydrocodone/guaifenesin

    This page was last edited on 21 December 2023, at 22:50 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply.

  9. Guaifenesin - Wikipedia

    en.wikipedia.org/wiki/Guaifenesin

    Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...