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Extensively drug-resistant tuberculosis (XDR-TB) is a form of tuberculosis caused by bacteria that are resistant to some of the most effective anti-TB drugs. XDR-TB strains have arisen after the mismanagement of individuals with multidrug-resistant TB (MDR-TB).
Some forms of TB are also resistant to second-line medications, and are called extensively drug-resistant TB . [1] Tuberculosis is caused by infection with the bacterium Mycobacterium tuberculosis. Almost one in four people in the world are infected with TB bacteria. [1] Only when the bacteria become active do people become ill with TB.
Extensively drug-resistant (XDR) is the non-susceptibility of one bacteria species to all antimicrobial agents except in two or less antimicrobial categories. Within XDR, pandrug-resistant (PDR) is the non-susceptibility of bacteria to all antimicrobial agents in all antimicrobial categories. [ 1 ]
“The discovery of any extensively antibiotic-resistant bacteria is alarming, especially in cities like Los Angeles,” said Henry Skinner, chief executive of the AMR Action Fund, ...
The CDC is warning about the rise of extensively drug-resistant shigella, which can cause bloody diarrhea. Here’s how to lower your risk of getting sick.
MDR-TB is defined as resistance to the two most effective first-line TB drugs: rifampicin and isoniazid. Extensively drug-resistant TB is also resistant to three or more of the six classes of second-line drugs. [155] Totally drug-resistant TB is resistant to all currently used drugs. [156]
The woman tested positive at the Basile facility again in September and was hospitalized for “pre-extensively drug-resistant TB,” which Murrill notes “is highly resistant to both first- and ...
As of October 2006, "Extensively drug-resistant tuberculosis" (XDR-TB) is defined as MDR-TB that is resistant to quinolones and also to any one of kanamycin, capreomycin, or amikacin. [76] The old case definition of XDR-TB is MDR-TB that is also resistant to three or more of the six classes of second-line drugs. [77]