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Loperamide/simethicone is combination medication sold under the brand name Imodium Multi-Symptom Relief (formerly Imodium A-D Advanced) used to treat diarrhea and gas simultaneously. It is manufactured by the McNeil Consumer Healthcare Division of McNeil PPC, Inc .
Decreasing intestinal motility prolongs the transit time of food content through the digestive tract, which allows for more fluid absorption; thereby alleviating diarrhea symptoms and improving stool consistency and frequency. [4] Unlike other opiates, loperamide does not cross the blood brain barrier, so there is minimal risk for abuse. [5]
Loperamide, sold under the brand name Imodium, among others, [1] is a medication of the opioid receptor agonist class used to decrease the frequency of diarrhea. [ 5 ] [ 4 ] It is often used for this purpose in irritable bowel syndrome , inflammatory bowel disease , short bowel syndrome , [ 4 ] Crohn's disease , and ulcerative colitis . [ 5 ]
Absorbents absorb toxic substances that cause infective diarrhoea, methylcellulose is an absorbent. Anti-inflammatory compounds such as bismuth subsalicylate. Anticholinergics reduce intestinal movement and are effective against both diarrhoea and accompanying cramping. Opioids' classical use besides pain relief is as an anti-diarrhoeal drug.
Antibiotics can also cause diarrhea, and antibiotic-associated diarrhea is the most common adverse effect of treatment with general antibiotics. While bismuth compounds (Pepto-Bismol) decreased the number of bowel movements in those with travelers' diarrhea, they do not decrease the length of illness. [112]
1. Luring “This is where you have a treat in your hand and you use it to guide your dog into specific positions,” explains DeWillems. “Luring can be pretty easy for most people and dogs to ...
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