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MCH is a cyclic 19-amino acid neuropeptide, as it is a polypeptide chain that is able to act as a neurotransmitter.MCH neurons are mainly concentrated in the lateral hypothalamic area, zona incerta, and the incerto-hypothalamic area, but they are also located, in much smaller amounts, in the paramedian pontine reticular formation (PPRF), medial preoptic area, laterodorsal tegmental nucleus ...
Several chemicals have been shown to be effective in skin whitening, while some have proven to be toxic or have questionable safety profiles. This includes mercury compounds which may cause neurological problems and kidney problems. [1] In a number of African countries, between 25 and 80% of women regularly use skin whitening products. [2]
Many forms of hyperpigmentation are caused by an excess production of melanin. [4] Hyperpigmentation can be diffuse or focal, affecting such areas as the face and the back of the hands. Melanin is produced by melanocytes at the lower layer of the epidermis. Melanin is a class of pigment responsible for producing color in the body in places such ...
But it’s believed to result from the skin’s pigment-producing cells being overactive and producing too much pigment or melanin. Dr. Rodney explains that melasma is much more common in women ...
2. Excessive Stress. Stress is a natural, normal part of the human experience, and your body knows how to handle it. When you’re under stress, your body releases stress hormones that activate ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 14 January 2025. "Skin pigmentation" redirects here. For animal skin pigmentation, see Biological pigment. Extended Coloured family from South Africa showing some spectrum of human skin coloration Human skin color ranges from the darkest brown to the lightest hues. Differences in skin color among ...
4. Stress. Stress can lead to overeating, eating high-calorie or high-fat foods, and sleep loss. When you’re stressed, the stress hormone cortisol reduces your brain’s sensitivity to leptin ...
Accumulation of melanin, the skin pigment; Accumulation of drug or one of its products under any layer of the skin (usually the dermis or epidermis) Accumulation of iron throughout the dermis from drug-induced post-inflammatory changes; The synthesis of special pigments, under direct influence of the drug