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The brain parenchyma refers to the functional tissue in the brain that is made up of the two types of brain cell, neurons and glial cells. [7] It is also known to contain collagen proteins. [8] Damage or trauma to the brain parenchyma often results in a loss of cognitive ability or even death.
The pathway consists of a para-arterial influx mechanism for CSF driven primarily by arterial pulsation, [2] which "massages" the low-pressure CSF into the denser brain parenchyma, and the CSF flow is regulated during sleep by changes in parenchyma resistance due to expansion and contraction of the extracellular space.
Scanning electron microscopy images have revealed that osteocytes possess numerous dendritic processes with expanded, endfoot-like structures. These endfeet directly abut and communicate with TCVs, establishing a close physical association that enables the transfer of mitochondria, and thereby provide the endothelial cells with the energy ...
The astrocytes of the glia limitans are responsible for separating the brain into two primary compartments. The first compartment is the immune-privileged brain and spinal cord parenchyma. This compartment contains multiple immunosuppressive cell surface proteins such as CD200 and CD95L and it allows for the release of anti-inflammatory factors.
PET image of the human brain showing energy consumption. The brain consumes up to 20% of the energy used by the human body, more than any other organ. [131] In humans, blood glucose is the primary source of energy for most cells and is critical for normal function in a number of tissues, including the brain. [132]
A 2-D model of cortical sensory homunculus. A cortical homunculus (from Latin homunculus 'little man, miniature human' [1] [2]) is a distorted representation of the human body, based on a neurological "map" of the areas and portions of the human brain dedicated to processing motor functions, and/ or sensory functions, for different parts of the body.
An organ's tissues can be broadly categorized as parenchyma, the functional tissue, and stroma, the structural tissue with supportive, connective, or ancillary functions. For example, the gland's tissue that makes the hormones is the parenchyma, whereas the stroma includes the nerves that innervate the parenchyma, the blood vessels that ...
The most prevalent anatomical region of neuropil is the brain which, although not completely composed of neuropil, does have the largest and highest synaptically concentrated areas of neuropil in the body. For example, the neocortex and olfactory bulb both contain neuropil. [1]