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  2. Elimination rate constant - Wikipedia

    en.wikipedia.org/wiki/Elimination_rate_constant

    t 1/2 is the half-life time of the drug, which is the time needed for the plasma drug concentration to drop to its half Therefore, the amount of drug present in the body at time t A t {\displaystyle A_{t}} is;

  3. Salicylate poisoning - Wikipedia

    en.wikipedia.org/wiki/Salicylate_poisoning

    Sodium bicarbonate is given in a significant aspirin overdose (salicylate level greater than 35 mg/dL 6 hours after ingestion) regardless of the serum pH, as it enhances elimination of aspirin in the urine. It is given until a urine pH between 7.5 and 8.0 is achieved.

  4. Aspirin-exacerbated respiratory disease - Wikipedia

    en.wikipedia.org/wiki/Aspirin-exacerbated...

    The recommended maintenance dose for symptom control is 650 mg to 1300 mg aspirin daily. [24] While on daily aspirin, patients experience improved quality of life and reduced nasal symptoms, however, there is no improvement in smell compared to placebo and there is no reduction in the need for oral corticosteroids or rescue surgery.

  5. Codeine - Wikipedia

    en.wikipedia.org/wiki/Codeine

    In Canada tablets containing 8 mg of codeine combined with 15 mg of caffeine and 300 mg of acetaminophen are sold as T1s (Tylenol Number 1) without a prescription. A similar tablet called "A.C. & C." (which stands for Acetylsalicylic acid with Caffeine and Codeine) containing 325–375 mg of acetylsalicylic acid (Aspirin) instead of ...

  6. Reye syndrome - Wikipedia

    en.wikipedia.org/wiki/Reye_syndrome

    Prevention is typically by avoiding the use of aspirin in children. [1] When aspirin was withdrawn for use in children in the US and UK in the 1980s, a decrease of more than 90% in rates of Reye syndrome was observed. [2] Early diagnosis of the syndrome improves outcomes. [1] Treatment is supportive; [1] mannitol may be used to help with the ...

  7. Percentage point - Wikipedia

    en.wikipedia.org/wiki/Percentage_point

    A percentage point or percent point is the unit for the arithmetic difference between two percentages.For example, moving up from 40 percent to 44 percent is an increase of 4 percentage points (although it is a 10-percent increase in the quantity being measured, if the total amount remains the same). [1]

  8. Paracetamol - Wikipedia

    en.wikipedia.org/wiki/Paracetamol

    Paracetamol's bioavailability is dose-dependent: it increases from 63 % for 500 mg dose to 89 % for 1000 mg dose. [6] Its plasma terminal elimination half-life is 1.9–2.5 hours, [6] and volume of distribution is roughly 50 L. [132] Protein binding is negligible, except under the conditions of overdose, when it may reach 15–21 %. [6]

  9. Pre-eclampsia - Wikipedia

    en.wikipedia.org/wiki/Pre-eclampsia

    Taking aspirin is associated with a 1 to 5% reduction in pre-eclampsia and a 1 to 5% reduction in premature births in women at high risk. [69] The World Health Organization recommends low-dose aspirin for the prevention of pre-eclampsia in women at high risk and recommends it be started before 20 weeks of pregnancy. [65]

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