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Buspirone, sold under the brand name Buspar among others, is an anxiolytic, a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder (GAD). [ 10 ] [ 11 ] It is a serotonin 5-HT 1A receptor partial agonist , increasing action at serotonin receptors in the brain. [ 3 ]
Buspar – an anxiolytic used to treat generalized anxiety disorder; Belbuca, Buprenex, Butrans, Subutex, Probuohine (buprenorphine) - an opioid medicine used to treat moderate to severe pain, and in some formulations to treat opioid use disorder; Belsomra – used to treat insomnia
Buspirone was originally classified as an azaspirodecanedione, shortened to azapirone or azaspirone due to the fact that its chemical structure contained this moiety, and other drugs with similar structures were labeled as such as well. However, despite all being called azapirones, not all of them actually contain the azapirodecanedione ...
Buspirone is sometimes used off-label to reduce sexual dysfunction associated with the use of SSRIs. [ 54 ] [ 55 ] [ 56 ] A number of non-SSRI drugs are not associated with sexual side effects (such as bupropion , mirtazapine , tianeptine , agomelatine , tranylcypromine , and moclobemide [ 57 ] [ 58 ] [ 59 ] ).
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The mechanism of action of bupropion in the treatment of depression and for other indications is unclear. [2] However, it is thought to be related to the fact that bupropion is a norepinephrine–dopamine reuptake inhibitor (NDRI) and negative allosteric modulator of several nicotinic acetylcholine receptors. [2]
The second-largest U.S. producer is partnering with investment firm Engine No. 1 and electric services company GE Vernova on the project. Chevron's announcement comes a day after Chinese startup ...
It uses data from federal agencies, scientists and other humanitarian organizations to produce a stream of reports on food security. USAID and humanitarian organizations used FEWS NET reports to ...