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The use of gold compounds has decreased since the 1980s because of numerous side effects and monitoring requirements, limited efficacy, and very slow onset of action. Most chemical compounds of gold, including some of the drugs discussed below, are not salts, but are examples of metal thiolate complexes .
Sodium aurothiomalate (INN, known in the United States as gold sodium thiomalate) is a gold compound that is used for its immunosuppressive anti-rheumatic effects. [ 2 ] [ 3 ] Along with an orally-administered gold salt, auranofin , it is one of only two gold compounds currently employed in modern medicine.
The gold atom centers in Au(III) complexes, like other d 8 compounds, are typically square planar, with chemical bonds that have both covalent and ionic character. Gold(I,III) chloride is also known, an example of a mixed-valence complex. Gold does not react with oxygen at any temperature [4] and, up to 100 °C, is resistant to attack from ...
Template:Gold compounds This page was last edited on 4 January 2024, at 11:49 (UTC). Text is available under the Creative Commons Attribution-ShareAlike 4.0 License ...
Nitratoauric acid, hydrogen tetranitratoaurate, or simply called gold(III) nitrate is a crystalline gold compound that forms the trihydrate, HAu(NO 3) 4 ·3H 2 O or more correctly H 5 O 2 Au(NO 3) 4 ·H 2 O. [3] [2] This compound is an intermediate in the process of extracting gold. [4] In older literature it is also known as aurinitric acid. [5]
Chloro(tetrahydrothiophene)gold(I), abbreviated (tht)AuCl, is a coordination complex of gold. Like the dimethyl sulfide analog , this compound is used as an entry point to gold chemistry. The tetrahydrothiophene ligand is labile and is readily substituted with other stronger ligands.
Sodium aurothiosulfate, or sanocrysin, is the inorganic compound with the formula Na 3 [Au(S 2 O 3) 2]·2H 2 O. It is the trisodium salt of the coordination complex of gold(I), [Au(S 2 O 3) 2] 3−. The dihydrate, which is colorless, crystallizes with two waters of crystallization. The compound has some medicinal properties as well as potential ...
Gold thioglucose features gold in the oxidation state of +I, like other gold thiolates. It is a water-soluble, non-ionic species that is assumed to exist as a polymer. [ 1 ] Under physiological conditions, an oxidation-reduction reaction leads to the formation of metallic gold and sulfinic acid derivative of thioglucose.