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Hypoxemic hypoxia is a lack of oxygen caused by low oxygen tension in the arterial blood, due to the inability of the lungs to sufficiently oxygenate the blood. Causes include hypoventilation, impaired alveolar diffusion, and pulmonary shunting. [8] This definition overlaps considerably with that of hypoxic hypoxia.
Tissue hypoxia refers to low levels of oxygen in the tissues of the body and the term hypoxia is a general term for low levels of oxygen. [2] Hypoxemia is usually caused by pulmonary disease whereas tissue oxygenation requires additionally adequate circulation of blood and perfusion of tissue to meet metabolic demands.
Generalized hypoxia is a medical condition in which the tissues of the body are deprived of the necessary levels of oxygen due to an insufficient supply of oxygen, which may be due to the composition or pressure of the breathing gas, decreased lung ventilation, or respiratory disease, any of which may cause a lower than normal oxygen content in the arterial blood, and consequently a reduced ...
The predominant symptoms of NC involve one or both legs and usually presents as some combination of tingling, cramping discomfort, pain, numbness, or weakness in the lower back, calves, glutes, and thighs and is precipitated by walking and prolonged standing. However, the symptoms vary depending on the severity and cause of the condition.
The classical explanation of HPV involves inhibition of hypoxia-sensitive voltage-gated potassium channels in pulmonary artery smooth muscle cells leading to depolarization. [ 3 ] [ 4 ] This depolarization activates voltage-dependent calcium channels , which increases intracellular calcium and activates smooth muscle contractile machinery which ...
The results may range from pain in the joints where the bubbles form to blockage of an artery(air bubble) [4] leading to damage to the fatigue, joint and muscle pain, clouded thinking, numbness, weakness, paralysis, rash, poor muscle coordination or balance, paralysis or death. While bubbles can form anywhere in the body, DCS is most frequently ...
Type I respiratory failure is caused by conditions that affect oxygenation and therefore lead to lower-than-normal oxygen in the blood. These include: Low ambient oxygen (e.g. at high altitude). [1] Ventilation-perfusion mismatch (parts of the lung receive oxygen but not enough blood to absorb it, e.g. pulmonary embolism, Acute respiratory ...
Hypopnea is overly shallow breathing or an abnormally low respiratory rate. Hypopnea is typically defined by a decreased amount of air movement into the lungs and can cause hypoxemia (low levels of oxygen in the blood.) It commonly is due to partial obstruction of the upper airway, but can also have neurological origins in central sleep apnea.
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