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Advanced glycation end products (AGEs) are proteins or lipids that become glycated as a result of exposure to sugars. [1] They are a bio-marker implicated in aging and the development, or worsening, of many degenerative diseases , such as diabetes , atherosclerosis , chronic kidney disease , and Alzheimer's disease .
Glycation is the non-enzymatic process responsible for many (e.g. micro and macrovascular) complications in diabetes mellitus and is implicated in some diseases and in aging. [ 2 ] [ 3 ] [ 4 ] Glycation end products are believed to play a causative role in the vascular complications of diabetes mellitus .
In a study from Switzerland, Grover's disease was diagnosed in just 24 of more than 30,000 skin biopsies. [4] Grover's disease is mainly seen in males over the age of forty. [13] Grover's disease affects chiefly white adults in the fifth decade or later, and appears to be around 1.6 to 2.1 times more common in men than in women.
The isoflavones within tofu support bone density, help protect against hormone-related cancers, help lower bad cholesterol, can help balance menopause symptoms, and combat oxidative stress, which ...
Aging skin is characterized by wrinkles, loss of skin flexibility, laxity, and having a rough appearance in the skin texture. Prevalent throughout the body, loss of collagen can also contribute to numerous other disorders such as joint pain , weakened hair and nails , reduced bone density , gastrointestinal issues , and reduced muscle mass .
Tell your doctor if you have any of the following signs or symptoms: redness or rash; itching; small bumps or patches; your skin is dry or feels like leather; blisters on the hands or feet that ...
Diabetic foot ulcer is a breakdown of the skin and sometimes deeper tissues of the foot that leads to sore formation. It is thought to occur due to abnormal pressure or mechanical stress chronically applied to the foot, usually with concomitant predisposing conditions such as peripheral sensory neuropathy, peripheral motor neuropathy, autonomic neuropathy or peripheral arterial disease. [1]
Phytophotodermatitis, also known as berloque dermatitis, [1] [2] [3] margarita photodermatitis, [4] [5] lime disease [6] or lime phytodermatitis [6] is a cutaneous phototoxic inflammatory reaction resulting from contact with a light-sensitizing botanical agent (such as lime juice) followed by exposure to ultraviolet A (UV-A) light (from the sun ...