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Adenosine triphosphate (ATP) is a nucleoside triphosphate [2] that provides energy to drive and support many processes in living cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis. Found in all known forms of life, it is often referred to as the "molecular unit of currency" for intracellular energy transfer. [3]
Yellapragada Subbarow [a] (12 January 1895 – 8 August 1948) was an Indian American biochemist who discovered the function of adenosine triphosphate (ATP) as an energy source in the cell, [1] developed methotrexate for the treatment of cancer and led the department at Lederle laboratories in which Benjamin Minge Duggar discovered chlortetracycline in 1945.
Phosphorus is a chemical element with the symbol P and the ... the industrially important pentasodium triphosphate ... For the use of phosphorus in drugs, detergents ...
Organophosphorus chemistry is the scientific study of the synthesis and properties of organophosphorus compounds, which are organic compounds containing phosphorus. [1] They are used primarily in pest control as an alternative to chlorinated hydrocarbons that persist in the environment.
The general formula of a phosphoric acid is H n−2x+2 P n O 3n−x+1, where n is the number of phosphorus atoms and x is the number of fundamental cycles in the molecule's structure; that is, the minimum number of bonds that would have to be broken to eliminate all cycles.
Bisphosphonates are popular drugs for treatment of osteoporosis. [1] Clodronic acid is a bisphosphonate used as a drug to treat osteoporosis. In biochemistry and medicinal chemistry, phosphonate groups are used as stable bioisosteres for phosphate, such as in the antiviral nucleotide analog, Tenofovir, one of the cornerstones of anti-HIV therapy.
The phosphate ion has a molar mass of 94.97 g/mol, and consists of a central phosphorus atom surrounded by four oxygen atoms in a tetrahedral arrangement. It is the conjugate base of the hydrogen phosphate ion [HPO 4 ] 2− , which in turn is the conjugate base of the dihydrogen phosphate ion [H 2 PO 4 ] − , which in turn is the conjugate ...
Hence, these drugs are usually taken with meals to bind any phosphate that may be present in the ingested food. Phosphate binders may be simple molecular entities (such as magnesium , aluminium , calcium , or lanthanum salts) that react with phosphate and form an insoluble compound.