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  2. Analysis of clinical trials - Wikipedia

    en.wikipedia.org/wiki/Analysis_of_clinical_trials

    A standard method to do this is the Last-Observation-Carried-Forward (LOCF) method. The LOCF method allows for the analysis of the data. However, recent research shows that this method gives a biased estimate of the treatment effect and underestimates the variability of the estimated result.

  3. Randomized controlled trial - Wikipedia

    en.wikipedia.org/wiki/Randomized_controlled_trial

    Peer review of results is an important part of the scientific method. Reviewers examine the study results for potential problems with design that could lead to unreliable results (for example by creating a systematic bias), evaluate the study in the context of related studies and other evidence, and evaluate whether the study can be reasonably ...

  4. Scientific method - Wikipedia

    en.wikipedia.org/wiki/Scientific_method

    The scientific method involves careful observation coupled with rigorous skepticism, because cognitive assumptions can distort the interpretation of the observation. Scientific inquiry includes creating a testable hypothesis through inductive reasoning , testing it through experiments and statistical analysis, and adjusting or discarding the ...

  5. Exploratory data analysis - Wikipedia

    en.wikipedia.org/wiki/Exploratory_data_analysis

    Tukey defined data analysis in 1961 as: "Procedures for analyzing data, techniques for interpreting the results of such procedures, ways of planning the gathering of data to make its analysis easier, more precise or more accurate, and all the machinery and results of (mathematical) statistics which apply to analyzing data." [3]

  6. Design of experiments - Wikipedia

    en.wikipedia.org/wiki/Design_of_experiments

    The use of a sequence of experiments, where the design of each may depend on the results of previous experiments, including the possible decision to stop experimenting, is within the scope of sequential analysis, a field that was pioneered [13] by Abraham Wald in the context of sequential tests of statistical hypotheses. [14]

  7. Study heterogeneity - Wikipedia

    en.wikipedia.org/wiki/Study_heterogeneity

    Meta-analysis is a method used to combine the results of different trials in order to obtain a quantitative synthesis. The size of individual clinical trials is often too small to detect treatment effects reliably. Meta-analysis increases the power of statistical analyses by pooling the results of all available trials.

  8. Methodology - Wikipedia

    en.wikipedia.org/wiki/Methodology

    A method is a structured procedure for bringing about a certain goal, like acquiring knowledge or verifying knowledge claims. This normally involves various steps, like choosing a sample, collecting data from this sample, and interpreting the data. The study of methods concerns a detailed description and analysis of these processes.

  9. Analytic and enumerative statistical studies - Wikipedia

    en.wikipedia.org/wiki/Analytic_and_enumerative...

    "The interpretation of results of a test or experiment is something else. It is prediction that a specific change in a process or procedure will be a wise choice, or that no change would be better. Either way the choice is prediction. This is known as an analytic problem, or a problem of inference, prediction." [4]