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The brain is resistant to acute iron deficiency due to the slow transport of iron through the blood brain barrier. [180] Acute fluctuations in iron status (marked by serum ferritin levels) do not reflect brain iron status, but prolonged nutritional iron deficiency is suspected to reduce brain iron concentrations over time.
The most common type is iron-deficiency anemia, in which a lack of iron leads to a reduction in the number of red blood cells or hemoglobin. This can impair oxygen transport throughout the body.
Neuroferritinopathy is a genetic neurodegenerative disorder characterized by the accumulation of iron in the basal ganglia, cerebellum, and motor cortex of the human brain. . Symptoms, which are extrapyramidal in nature, progress slowly and generally do not become apparent until adulthood
Neurodegeneration with brain iron accumulation is a heterogenous group of inherited neurodegenerative diseases, still under research, in which iron accumulates in the basal ganglia, either resulting in progressive dystonia, parkinsonism, spasticity, optic atrophy, retinal degeneration, neuropsychiatric, or diverse neurologic abnormalities. [1]
Iron is also stored as a pigment called hemosiderin, which is an ill-defined deposit of protein and iron, created by macrophages where excess iron is present, either locally or systemically, e.g., among people with iron overload due to frequent blood cell destruction and the necessary transfusions their condition calls for. If systemic iron ...
A boot sector computer virus dubbed (c)Brain, one of the first computer viruses in history, [16] was created in 1986 by the Farooq Alvi Brothers in Lahore, Pakistan, reportedly to deter unauthorized copying of the software they had written. [17] [18] Neurochip by Pakistani-Canadian inventor Naweed Syed.
The Urdu Wikipedia (Urdu: اردو ویکیپیڈیا), started in January 2004, is the Standard Urdu-language edition of Wikipedia, a free, open-content encyclopedia. [1] [2] As of 19 February 2025, it has 217,936 articles, 190,727 registered users and 7,544 files, and it is the 54th largest edition of Wikipedia by article count, and ranks 20th in terms of depth among Wikipedias with over ...
The type of neurological disruption corresponds to associated regions of iron deposition in the brain and liver. [5] In addition to neurological problems, affected individuals may have diabetes mellitus caused by iron damage to cells in the pancreas that make insulin. This impairs blood sugar regulation and leads to the signs and symptoms of ...