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The diagrams below take inter-cycle and inter-woman variability into account in displaying reference ranges for estradiol, progesterone, FSH and LH. Levels of estradiol (the main estrogen), progesterone, luteinizing hormone and follicle-stimulating hormone during the menstrual cycle. [88]
Diagnostic workup includes a detailed history and physical, laboratory studies, such as a pregnancy test, and serum levels of FSH and LH, prolactin, and thyroid-stimulating hormone (TSH), and imaging. [7] Additional tests may be indicated in order to distinguish FHA from organic hypothalamic or pituitary disorders.
Luteinizing hormone receptors are located in areas of the brain associated with cognitive function. [28] The role of LH role in the central nervous system (CNS) may be of relevance to understanding and treating post-menopausal cognitive decline. [29] Some research has observed an inverse relationship between circulating LH and CNS LH levels. [30]
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The stages of the menopause transition have been classified according to a woman's reported bleeding pattern, supported by changes in the pituitary follicle-stimulating hormone (FSH) levels. [57] In younger women, during a normal menstrual cycle the ovaries produce estradiol, testosterone and progesterone in a cyclical pattern under the control ...
In women, the diagnosis of LH/FSH deficiency depends on whether the woman has been through the menopause. Before the menopause, abnormal menstrual periods together with low estradiol and LH/FSH levels confirm a pituitary problem; after the menopause (when LH/FSH levels are normally elevated and the ovaries produce less estradiol ...
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