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Wolfram syndrome, also called DIDMOAD ( d iabetes i nsipidus, d iabetes m ellitus, o ptic a trophy, and d eafness), is a rare autosomal-recessive genetic disorder that causes childhood-onset diabetes mellitus, optic atrophy, and deafness as well as various other possible disorders including neurodegeneration. [2] [3] [4]
Specialty: Endocrinology: Symptoms: Enlargement of the hands, feet, forehead, jaw, and nose, thicker skin, deepening of the voice: Complications: Type 2 diabetes, sleep apnea, high blood pressure, high cholesterol, heart problems, particularly enlargement of the heart (cardiomyopathy), osteoarthritis, spinal cord compression or fractures, increased risk of cancerous tumors, precancerous ...
Diabetes insipidus ( DI ), alternately called arginine vasopressin deficiency (AVP-D) or arginine vasopressin resistance (AVP-R), [5] is a condition characterized by large amounts of dilute urine and increased thirst. [1] The amount of urine produced can be nearly 20 liters per day. [1] Reduction of fluid has little effect on the concentration ...
Diabetic dermopathy is a type of skin lesion usually seen in people with diabetes mellitus. It is characterized by dull-red papules that progress to well-circumscribed, small, round, atrophic hyperpigmented skin lesions usually on the shins. It is the most common [1] : 540 [2] : 681 of several diabetic skin conditions, being found in up to 30% ...
Nephrogenic diabetes insipidus, recently renamed arginine vasopressin resistance (AVP-R) and previously known as renal diabetes insipidus, is a form of diabetes insipidus primarily due to pathology of the kidney. This is in contrast to central or neurogenic diabetes insipidus, which is caused by insufficient levels of vasopressin (also called ...
Diabetic cheiroarthropathy, also known as diabetic stiff hand syndrome or limited joint mobility syndrome, is a cutaneous condition characterized by waxy, thickened skin and limited joint mobility of the hands and fingers, leading to flexion contractures, a condition associated with diabetes mellitus: 681 and it is observed in roughly 30% of diabetic patients with longstanding disease.
Necrobiosis lipoidica is a rare, chronic skin condition predominantly associated with diabetes mellitus (known as necrobiosis lipoidica diabeticorum or NLD ). [1] It can also occur in individuals with rheumatoid arthritis or without any underlying conditions ( idiopathic ). [2] It is characterized by hardened, raised areas of the skin, often ...
Diabetic dermadrome. Diabetic dermadromes constitute a group of cutaneous conditions commonly seen in people with diabetes with longstanding disease. [1] Conditions included in this group are: [1] [2] Limited joint mobility is observed in roughly 30% of people with diabetes with longstanding disease. [1]
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