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Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease, also known as pseudogout and pyrophosphate arthropathy, is a rheumatologic disease which is thought to be secondary to abnormal accumulation of calcium pyrophosphate dihydrate crystals within joint soft tissues. [1] The knee joint is most commonly affected. [2]
Crystal arthropathy is a class of joint disorder (called arthropathy) that is characterized by accumulation of tiny crystals in one or more joints. Polarizing microscopy and application of other crystallographic techniques have improved identification of different microcrystals including monosodium urate , calcium pyrophosphate dihydrate ...
Crystal Analysis: Using a microscope and polarizing light filter, birefringence of crystals can be detected in a sample of synovial fluid. This is essential to distinguish monosodium urate crystals in gout from calcium pyrophosphate dihydrate crystals in pseudogout .
In pseudogout, a form of calcium crystals accumulate in joint cartilage and fluid, causing the same sudden joint pain and swelling as gout. Pseudogout typically affects people over the age of 60 ...
For example, gout in ankles or gout in knee joints may also occur. Gout in hands is less common but can happen. In this situation, it usually affects small joints in the fingers.
Pseudogout (also referred to as calcium pyrophosphate dihydrate crystal deposition disease) is another type of crystalline arthritis that presents very similarly to gout but is caused by the deposition of rhomboid-shaped calcium pyrophosphate dihydrate (CPPD) crystals. The knees, wrists, and fingers are the most common joints affected by ...
712 Crystal arthropathies. 712.1 Chondrocalcinosis due to dicalcium phosphate crystals; 712.2 Chondrocalcinosis due to pyrophosphate crystals; 712.3 Chondrocalcinosis, cause unspecified pseudogout; 712.8 Other specified crystal arthropathies; 712.9 Unspecified crystal arthropathy; 713 Arthropathy, endocrine disorders. 713.1 Arthropathy ...
For example, mechanical obstruction by mineral stones causes nephrolithiasis, urolithiasis, cholecystolithiasis, choledocholithiasis, docholithiasis, and sialolithiasis, and acute inflammation caused by crystals in joints causes gout and pseudogout. [1] Renal diseases are also common in crystallopathies, including: [1]