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Bordetella pertussis is a Gram-negative, aerobic, pathogenic, encapsulated coccobacillus bacterium of the genus Bordetella, and the causative agent of pertussis or whooping cough. Its virulence factors include pertussis toxin , adenylate cyclase toxin , filamentous haemagglutinin , pertactin , fimbria , and tracheal cytotoxin .
Whooping cough is a highly contagious bacterial infection that affects children and adults alike - though it's more common and concerning in infants and toddlers. The infection primarily affects ...
Bordetella (/ ˌ b ɔːr d ə ˈ t ɛ l ə /) is a genus of small (0.2 – 0.7 μm), Gram-negative, coccobacilli bacteria of the phylum Pseudomonadota. Bordetella species, with the exception of B. petrii, are obligate aerobes, as well as highly fastidious, or difficult to culture.
Whooping cough (/ ˈ h uː p ɪ ŋ / or / ˈ w uː p ɪ ŋ /), also known as pertussis or the 100-day cough, is a highly contagious, vaccine-preventable bacterial disease. [1] [10] Initial symptoms are usually similar to those of the common cold with a runny nose, fever, and mild cough, but these are followed by two or three months of severe coughing fits. [1]
Whooping cough bacteria Bordetella pertussis in human airways; nurse prepares syringe with vaccine against whooping cough; Migrants from the southern border being dropped of at Trenton ...
The DPT vaccine or DTP vaccine is a class of combination vaccines to protect against three infectious diseases in humans: diphtheria, pertussis (whooping cough), and tetanus (lockjaw). [7] The vaccine components include diphtheria and tetanus toxoids , and either killed whole cells of the bacterium that causes pertussis or pertussis antigens .
Whooping cough, a respiratory infection that is particularly deadly for infants, has been relatively calm since a 2019 outbreak in California, but officials fear a return.
Pertussis was well known throughout Europe by the middle of the 18th century. Jules Bordet and Octave Gengou described in 1900 the finding of a new “ovoid bacillus” in the sputum of a 6-month-old infant with whooping cough. They were also the first to cultivate Bordetella pertussis at the Pasteur Institute in Brussels in 1906. [9]