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Ménière's disease (MD) is a disease of the inner ear that is characterized by potentially severe and incapacitating episodes of vertigo, tinnitus, hearing loss, and a feeling of fullness in the ear. [3] [4] Typically, only one ear is affected initially, but over time, both ears may become involved. [3]
A 2018 study from Korea found the chance of progression to Meniere's disease of all participants with SLFHL to be 9.38% with an average progression time of 1.7±1.4 years, but when limited to patients with recurring symptoms "it was confirmed that about half (46.88%) of them progressed to Meniere's disease."
Ménière's disease frequently presents with recurrent, spontaneous attacks of severe vertigo in combination with ringing in the ears , a feeling of pressure or fullness in the ear (aural fullness), severe nausea or vomiting, imbalance, and hearing loss. [9] [25] [38] As the disease worsens, hearing loss will progress.
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Around the 28th day, parts of the otic vesicle begin to form the vestibulocochlear nerve. [20] [22] These form bipolar neurons, which supply sensation to parts of the inner ear (namely the sensory parts of the semicircular canals, macular of the utricle and saccule, and organ of Corti). [20] Around the 33rd day, the vesicles begin to differentiate.
Prosper Menière (18 June 1799 – 7 February 1862) was a French medical doctor who first identified that the inner ear could be the source of a condition combining vertigo, hearing loss and tinnitus, [1] which is now known as Ménière's disease.
Betahistine, sold under the brand name Serc among others, is an anti-vertigo medication.It is commonly prescribed for balance disorders or to alleviate vertigo symptoms.It was first registered in Europe in 1970 for the treatment of Ménière's disease, but current evidence does not support its efficacy in treating it.
Endolymphatic hydrops may occur as a result of trauma such as a blow to the head, infection, degeneration of the inner ear, allergies, dehydration and loss of electrolytes or in extremely rare circumstances a benign tumor such as an endolymphatic sac tumor. [2]
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