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  2. Neighbouring group participation - Wikipedia

    en.wikipedia.org/wiki/Neighbouring_group...

    In this type of substitution reaction, one group of the substrate participates initially in the reaction and thereby affects the reaction. A classic example of NGP is the reaction of a sulfur or nitrogen mustard with a nucleophile, the rate of reaction is much higher for the sulfur mustard and a nucleophile than it would be for a primary or secondary alkyl chloride without a heteroatom.

  3. Integration by substitution - Wikipedia

    en.wikipedia.org/wiki/Integration_by_substitution

    In calculus, integration by substitution, also known as u-substitution, reverse chain rule or change of variables, [1] is a method for evaluating integrals and antiderivatives. It is the counterpart to the chain rule for differentiation , and can loosely be thought of as using the chain rule "backwards."

  4. List of reagents - Wikipedia

    en.wikipedia.org/wiki/List_of_reagents

    is an alkaline solution of potassium permanganate; used in organic chemistry as a qualitative test for the presence of unsaturation, such as double bonds; N-Bromosuccinimide: used in radical substitution and electrophilic addition reactions in organic chemistry. Also acts as a mild oxidizer to oxidize benzylic or allylic alcohols.

  5. Rate-determining step - Wikipedia

    en.wikipedia.org/wiki/Rate-determining_step

    Another example is the unimolecular nucleophilic substitution (S N 1) reaction in organic chemistry, where it is the first, rate-determining step that is unimolecular. A specific case is the basic hydrolysis of tert-butyl bromide (t-C 4 H 9 Br) by aqueous sodium hydroxide. The mechanism has two steps (where R denotes the tert-butyl radical t-C ...

  6. Substitution reaction - Wikipedia

    en.wikipedia.org/wiki/Substitution_reaction

    Substitution reactions in organic chemistry are classified either as electrophilic or nucleophilic depending upon the reagent involved, whether a reactive intermediate involved in the reaction is a carbocation, a carbanion or a free radical, and whether the substrate is aliphatic or aromatic. Detailed understanding of a reaction type helps to ...

  7. Integration by reduction formulae - Wikipedia

    en.wikipedia.org/wiki/Integration_by_reduction...

    In integral calculus, integration by reduction formulae is a method relying on recurrence relations.It is used when an expression containing an integer parameter, usually in the form of powers of elementary functions, or products of transcendental functions and polynomials of arbitrary degree, can't be integrated directly.

  8. Reactions of organocopper reagents - Wikipedia

    en.wikipedia.org/wiki/Reactions_of_organocopper...

    Organocopper reagents are now commonly used in organic synthesis as mild, selective nucleophiles for substitution and conjugate addition reactions. [ 1 ] Since the discovery that copper(I) halides catalyze the conjugate addition of Grignard reagents in 1941, [ 2 ] organocopper reagents have emerged as weakly basic, nucleophilic reagents for ...

  9. Tangent half-angle substitution - Wikipedia

    en.wikipedia.org/.../Tangent_half-angle_substitution

    The substitution is described in most integral calculus textbooks since the late 19th century, usually without any special name. [5] It is known in Russia as the universal trigonometric substitution , [ 6 ] and also known by variant names such as half-tangent substitution or half-angle substitution .