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Ivermectin is an antiparasitic drug. [7] After its discovery in 1975, [8] its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. [9] Approved for human use in 1987, [10] it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis.
The medication ivermectin is widely used to treat strongyloidiasis. Strongyloidiasis is a type of soil-transmitted helminthiasis . Low estimates postulate it to affect 30–100 million people worldwide, [ 1 ] mainly in tropical and subtropical countries, while higher estimates conservatively extrapolate that infection is upwards to or above 370 ...
Fasciola hepatica, also known as the common liver fluke or sheep liver fluke, is a parasitic trematode (fluke or flatworm, a type of helminth) of the class Trematoda, phylum Platyhelminthes. It infects the livers of various mammals , including humans, and is transmitted by sheep and cattle to humans all over the world.
The product, Fasiject Plus, a triclabendazole 36% and ivermectin 0.6% solution, is designed to treat infections by Fasciola hepatica (both immature and adult liver flukes), roundworms and ectoparasites, as well. [citation needed] Fasinex is a brand name for veterinary use while Egaten is a brand name for human use. [citation needed]
Helminthiasis, also known as worm infection, is any macroparasitic disease of humans and other animals in which a part of the body is infected with parasitic worms, known as helminths. There are numerous species of these parasites , which are broadly classified into tapeworms , flukes , and roundworms .
These drugs are used to kill the parasites that live on the body surface. Permethrin, sulfur, lindane, dicophane, benzyl benzoate, ivermectin and crotamiton are well known ectoparasiticides. [2] Additionally, ectoparasiticides have been used to safely contaminate rhinoceros horns with hopes of it deterring the demand for these horns on the ...
In humans, the onset of cholangiocarcinoma occurs with chronic opisthorchiasis, associated with hepatobiliary damage, inflammation, periductal fibrosis and/or cellular responses to antigens from the infecting fluke. [5] These conditions predispose to cholangiocarcinoma, possibly through an enhanced susceptibility of DNA to damage by carcinogens.
Liver flukes infect all grazing animals and infect humans when they eat raw or undercooked fish. Like other flukes, the liver flukes need intermediate hosts and as a result, the transmission from animals to humans happens in three phases. The first phase is the infection of the snail (the first intermediate host) via feces.
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