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Multifocal motor neuropathy (MMN) is a progressively worsening condition where muscles in the extremities gradually weaken. The disorder, a pure motor neuropathy syndrome, is sometimes mistaken for amyotrophic lateral sclerosis (ALS) because of the similarity in the clinical picture, especially if muscle fasciculations are present.
Any condition resulting in decreased peripheral sensation, proprioception, and fine motor control: Diabetes mellitus neuropathy (the most common in the U.S. today, resulting in destruction of foot and ankle joints), with Charcot joints in 1/600–700 diabetics; related to long-term high blood glucose levels. Alcoholic neuropathy; Cerebral palsy ...
They are the terminal ends of the L1-L3 spinal nerve dorsal rami lateral branches. They are one of three different types of cluneal nerves (the middle and inferior cluneal nerves being the other two). They travel inferiorly through multiple layers of muscles, then traverse osteofibrous tunnels between the thoracolumbar fascia and iliac crest.
It is a neurological and orthopedic condition that affects the motor nervous system of the body, specifically, the lower back, legs, hips and glutes. [ 5 ] [ 6 ] NC does not occur by itself, but rather, is associated with other underlying spinal or neurological conditions such as spinal stenosis or abnormalities and degenerative changes in the ...
Spinal and bulbar muscular atrophy; Spinal cord injury; Spinal cord tumors; Spinal muscular atrophy; Spinal muscular atrophy with respiratory distress type 1 – see Distal spinal muscular atrophy type 1; Spinocerebellar ataxia; Split-brain; Steele–Richardson–Olszewski syndrome – see Progressive supranuclear palsy; Stiff-person syndrome ...
The obturator nerve is responsible for the sensory innervation of the skin of the medial aspect of the thigh.. The nerve is also responsible for the motor innervation of the adductor muscles of the lower limb (external obturator, [4] adductor longus, adductor brevis, adductor magnus, gracilis) and the pectineus (inconstant).
Additionally, BP control in those with diabetes is helpful, while intravenous immunoglobulin is used for multifocal motor neuropathy. [1] According to Lopate, et al., methylprednisolone is a viable treatment for chronic inflammatory demyelinative polyneuropathy (which can also be treated with intravenous immunoglobulin).
In general, distal hereditary motor neuropathies affect the axons of distal motor neurons and are characterized by progressive weakness and atrophy of muscles of the extremities. [1] It is common for them to be called "spinal forms of Charcot-Marie-Tooth disease (CMT)", because the diseases are closely related in symptoms and genetic cause.