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Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. [1] It is used to treat chronic obstructive pulmonary disease (COPD) and asthma . [ 2 ]
J. Allende publishes a book describing the treatment of gastric ulcers with penicillin. [2] 1953 Dintzis and Hastings are able to stop urease production in mice with antibiotics, suggesting a relationship between urease and a bacterial infection. [19] 1954 Palmer publishes a study which finds no bacteria in the human stomach.
Cancer of the stomach is difficult to cure unless it is found at an early stage (before it has begun to spread). Unfortunately, because early stomach cancer causes few symptoms, the disease is usually advanced when the diagnosis is made. [80] Treatment for stomach cancer may include surgery, [81] chemotherapy, [13] or radiation therapy. [82]
Woman diagnosed with stomach cancer after experiencing severe heartburn. Doctors dismissed her symptoms and the cancer later spread to her ovaries. Woman, 39, thought her severe heartburn was a ...
1900 – Swedish Dr. Stenbeck cures a skin cancer with small doses of radiation [4]; 1920s – Dr. William B. Coley's immunotherapy treatment, regressed tumors in hundreds of cases, the success of Coley's Toxins attracted heavy resistance from his rival and supervisor, Dr. James Ewing, who was an ardent supporter of radiation therapy for cancer.
Cimetidine was the prototypical histamine H 2 receptor antagonist from which later drugs were developed. Cimetidine was the culmination of a project at Smith, Kline & French (SK&F; now GlaxoSmithKline) by James W. Black, C. Robin Ganellin, and others to develop a histamine receptor antagonist that would suppress stomach acid secretion.
Like other methylated xanthine derivatives, pentoxifylline is a competitive nonselective phosphodiesterase inhibitor [20] which raises intracellular cAMP, activates PKA, inhibits TNF [21] [22] and leukotriene [23] synthesis, and reduces inflammation and innate immunity. [23]
Many U.S. states, however, remain as loyal to abstinence-only treatment as Kentucky does, and not enough doctors are willing to prescribe the medications. In a University of Washington study released this month, based on 2012 data, researchers found that 30 million Americans lived in counties without a single doctor certified to prescribe Suboxone.
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