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Intradural-extramedullary tumors are often benign, so observation with follow-up imaging is an option in cases where the lesions are small and the patient is asymptomatic. [4] Radiotherapy and chemotherapy may be administered alone or in conjunction with surgery.
A myeloid sarcoma (chloroma, granulocytic sarcoma, [1]: 744 extramedullary myeloid tumor) is a solid tumor composed of immature white blood cells [2] called myeloblasts. A chloroma is an extramedullary manifestation of acute myeloid leukemia ; in other words, it is a solid collection of leukemic cells occurring outside of the bone marrow .
The proposed criteria for SPB is the presence of a single bone lesion, normal bone marrow (less than 5% plasma cells), small or no paraprotein, no related organ involvement/damage and a normal skeletal survey (other than the single bone lesion). The criteria for extramedullary plasmacytoma are the same but the tumor is located in soft tissue.
Extramedullary hematopoiesis (EMH or sometimes EH [1]) refers to hematopoiesis occurring outside of the medulla of the bone (bone marrow). [2] It can be physiologic or pathologic. Physiologic EMH occurs during embryonic and fetal development; during this time the main site of fetal hematopoiesis are liver and the spleen.
Spinal nerve sheath tumors generally arise as single lesions. [1] Presence of multiple lesions is associated with genetic conditions including neurofibromatosis type 1, neurofibromatosis type 2, and Schwannomatosis. [1] [3] [4] Most spinal schwannomas are intradural-extramedullary, growing inside the thecal sac, but outside the spinal cord ...
Intramedullary is a medical term meaning the inside of a bone. Examples include intramedullary rods used to treat bone fractures in orthopedic surgery and intramedullary tumors occurring in some forms of cancer or benign tumors such as an enchondroma .
Either 1) brain MRI showing normal findings or only nonspecific white matter lesions, or 2) optic nerve MRI showing T2-hyperintensity, or T1 enhancing lesion, greater than 1/2 optic nerve length or involving optic chiasm Acute myelitis: intramedullary lesion > 3 contiguous segments, or spinal atrophy ≥ 3 contiguous segments
Blueberry muffin lesions in the neonate indicate the prolongation of dermal extramedullary hematopoiesis outside of the gestational period. [ 3 ] The blueberry muffin rash was originally considered pathognomonic of congenital rubella , but it is now considered to be potentially associated with many other intrauterine infections, hematologic ...